Studies on the determination of blood lead by neopolarographic anodic stripping voltammetry

Abstract

The present paper presents an analytical method for the determination of trace lead in blood by neopolarographic anodic stripping voltammetry with a glass carbon mercury film electrode. High-pressure wet digestion has been used for the pretreatment of blood samples. The trace lead can be determined in a 0.1 M HAc −0.1 M NaAc and 5×10⁻⁵ M Hg(NO₃)₂ medium with one drop of finger blood (0.020–0.050 ml). The limit of detection is 7.5 ×10⁻¹¹ g/ml. The method has been applied to the determination of trace lead in blood samples of 41 healthy persons, 44 occupationally lead-exposed workers and 33 policemen on duty controlling the traffic for a period of more than 8 years. The results obtained showed no difference to those reported in the literature.

Keywords

lead / blood / pretreatment / neopolarography

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