Reinnervation of free transferred muscle by nerve suture and nerve implantation in combination—An experimental study

Abstract

The authors have designed a method of combining nerve suture and nerve implantation to improve reinnervation and functional recovery of free transferred muscles. Experimental results on EMG recording, muscle power, muscle weight and histologic construction showed better recovery, compared with either mere nerve suture or nerve implantation. The change of motor end-plates with cholinesterase staining indicates more perfect reinnervation. The clinical significance of this method and certain considerations in performance are discussed in this paper.

Keywords

free transferred muscle / nerve suture / nerve implantation / reinnervation

References

[1.] FreyM, et al. . Experimental comparison of the different kinds of muscle reinnervation: nerve suture, nerve implantation, and muscular neurotization. Plast Reconstr Surg., 1982, 69: 656-69

[2.] FaulknerJA, et al. . Skeletal muscle transplantation in cats with and without nerve repair, 1981, New York, Springer-Verlag: 47-54

[3.] TerzisJK, et al. . Recovery of function in free muscle transplantation using microneurovascular anastomoses. J Hand Surg., 1978, 3: 37-59

[4.] SorbicC, et al. . Reinnervation of paralysed muscles by direct nerve implantation. J Bone Joint Surg., 1968, 51: 156-64

[5.] KarpatiG, et al. . “Type grouping” in skeletal muscles after experimental reinnervation. Neurology., 1968, 18: 447-51

[6.] GuthL, et al. . Disposition of cholinesterase following implantation of nerve into innervated and denervated muscle. Exp Neuro., 1963, 7: 316-26

[7.] FrankE, et al. . The interaction between foreign and original motor nerves innervating the soleus muscle of rats. J Physiol., 1975, 247: 725-32

[8.] FexS, et al. . Nerve implants in botulinum poisoned mammalian muscle. J Physiol., 1966, 184: 872-8