Studies on anti-infective mechanism of the traditional Chinese medicinal preparation “Anti-inflammatory Agent No. 6” — Its influence on immune functions of mice

Abstract

The traditional Chinese medicinal preparation “Anti-inflammatory Agent No.6” (for injection) could raise the phagocytic index and phagocytic rate of the peritoneal macrophages by 2.5 and 3 times respectively in experimental mice, and it could also enhance the activity of complement alternative pathway evidently. However, the serum lysozyme level did not rise unless a large doss of it was given. It was also shown by the measurement of the spleen cell immune specific RFC (IRFC), quantitative hemolysis of SRBC and anti-SRBC antibodies that this preparation promoted the specific humoral immunity at different stages of immune response in mice. The results of cellular immunity tests also revealed that it had an obvious influence upon the delayed hypersensitive reaction as well as on the number of ANAE-positive cells in the peripheral blood. The preparation was proved to have a good anti-infective effect, for it could regulate and enhance a variety of immune functions.

Keywords

Anti-inflammatory Agent No.6 / complement alternative pathway / phagocytic index / immune specific RFC / contact superallergic reaction

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