Surgical treatment of myasthenia gravis and evaluation of its efficacy

Pan Tie-cheng , Chen Qi-fu , Zhang Liang-hua , Shen Yuan-zhong , Xie Zhao-ping , Yang Ming-shan , Bu Bi-tao , Cao Xue-bing

Current Medical Science ›› 1991, Vol. 11 ›› Issue (2) : 106 -110.

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Current Medical Science ›› 1991, Vol. 11 ›› Issue (2) : 106 -110. DOI: 10.1007/BF02888097
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Surgical treatment of myasthenia gravis and evaluation of its efficacy

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Abstract

This paper reports 30 cases of myasthenia gravis (MG) treated by thymectomy from 1965 to 1990 in our hospital. Of all the 30 cases of MG, peripheral blood lymphocyte subpopulation was determined in 10, and anti-acetylcholine receptor antibody titer in 6, before and after operation. The results demonstrated the efficacy of thymectomy against MG. We considered that with application of hormone before and after operation to regulate immune function of the body, and/or with plasma exchange to remiss symptoms, all the patients with generalized MG may be indicated for treatment by thymectomy. Indication of treatment does not depend on age, sex and the course of the disease. But radical operation, proper anesthesia and appropriate use of antibiotics may ensure safety of the operation and its curative effect.

Keywords

myasthenia gravis / surgical treatment / efficacy

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Pan Tie-cheng, Chen Qi-fu, Zhang Liang-hua, Shen Yuan-zhong, Xie Zhao-ping, Yang Ming-shan, Bu Bi-tao, Cao Xue-bing. Surgical treatment of myasthenia gravis and evaluation of its efficacy. Current Medical Science, 1991, 11(2): 106-110 DOI:10.1007/BF02888097

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BerrihS, et al.. Depletion of helper/inducer T cells after thymectomy in myasthenic patients. Clin Immunol Immunopathol, 1983, 28: 272-81

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