Effect of intra-arachnoid space perfusion on thromboxane a and prostacycline in experimental spinal cord injury

Abstract

In order to understand the relation between TXA₂- PGI₂ and secondary trauma and the effect of intra-arachnoid perfusion of dexamethasone and verapamil on alteration of TXA₂-PGI₂ following spinal cord injury, TXB₂ and 6-keto-PGF. concentration and pathological changes in injured site 1, 2, 4 and 6 h after injury were studied using a rabbit spinal cord injury model by Allen’s weight drop method.

Keywords

subarachnoid cavity / thromboxane A / prostacycline / experimental spinal cord injury

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