Effect of dexamethasone on Glu-IR and GABA-IR neurons of hippocampus in rats

Abstract

Dexamethasone (Dex) was injected into the rat lateral ventricle and the changes of glutamate-imrnunoreactivity (Glu-IR) and γ-aminobulyric acid immunoreactivity (GABA-IR) neurons in the hippocampus were immunocytochemically examined 2 h after injection. The results showed that Glu-IR neurons increased and GABA-IR neurons did not show marked change. The mechanism remains to be further studied.

Keywords

dexamethasone / hippocampus / neurotransmitter

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