Immunoregulatory effects of indomethacin on rats with trauma

Abstract

In this article, we invertigated changes of immune functions and immunoregulatory effects of indomethacin on rats with trauma. The results show that spontaneous suppressor T cell activity of spleen significantly increased and Interleukin 2 production and DNA synthesis capacity of splenocytes markedly decreased in rats with trauma. Indomethacin could markedly improve immune function, decreased spontancous suppressor T cell activity and prompted Interleukin 2 production and DNA synthesis capacity of splenocytes.

Keywords

trauma / spontaneous suppressor T cell / interleukin 2 / immunoregulation / indomethacin

References

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