Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression

Li Hua; Xiong Shu-tao; Zhang Shou-xi; Liu Shao-bin; Luo Yi

doi:10.1007/BF02887817

Current Medical Science ›› 1992, Vol. 12 ›› Issue (3) : 160 -163. DOI: 10.1007/BF02887817

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Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression

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Abstract

To elucidate the mechanism of immunologic abnormalities induced by surgical trauma, we measured interleukin 2 (IL-2) production and IL-2 receptor expression in peripheral blood mononuclear cells from 16 patients with cholelithiasis. Compared with preoperative levels, IL-2 production and IL-2 receptor expression were significantly reduced on postoperative day 4, and the reduction was consistent with the suppression of lymphocyte proliferative response to phytohemagglutinin.

Keywords

surgical trauma / interleukin 2 / interleukin 2 receptor / lymphocyte proliferation

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Li Hua, Xiong Shu-tao, Zhang Shou-xi, Liu Shao-bin, Luo Yi. Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression. Current Medical Science, 1992, 12(3): 160-163 DOI:10.1007/BF02887817

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