Effects of sustained Ligustrazine on hemorrheology in patients with chronic pulmonary heart disease

Abstract

Before and after oral administration of sustained Ligustrazine, changes of hemorrheology and TXA₂/PGI₂ were evaluated in 16 patients with advanced chronic pulmonary heart disease. A decrease in whole blood and plasma viscosity, and reductions in hematocrit and fibrinogen were found after one course of treatment with sustained Ligustrazine. The mechanism of these effects may be related to improved modulation of imbalance of TXA₂/PGI₂ in patients with advanced chronic pulmonary heart disease.

Keywords

chronic pulmonary heart disease / hemorrheology / Ligustrazine

References

[1] 1988;17(4):279.

[2] 1987;7(1):26.

[3] 1990, 21

[4] 1987; 67(11):607.

[5] 1977; 57:464.

[6] 1978; 6:41.

[7] 1977, 4:117.