Expression of telomerase gene mTR in the testis of SD rats and its significance

Fan Min; Chen Xiaochun; Ye Zhewei; Xiong Yali; Zeng Fuqing; Lu Gongcheng

doi:10.1007/BF02859948

Current Medical Science ›› 2003, Vol. 23 ›› Issue (23) : 173 -175. DOI: 10.1007/BF02859948

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Expression of telomerase gene mTR in the testis of SD rats and its significance

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Abstract

To study the expression of mTR gene in the testis of SD rats with varied ages and its significance,in situ hybridization (ISH) techniques were applied to detect the expression of telomerase gene mTR mRNA in the testis of SD rats. The expression of mTR was found in testes of differentage male SD rats. There was a positive correlation between the expression of mTR and the location of germ cells (spermatogonia, spermatocyte, spermatid). In Setoli cells, leydig cell and spermatozoa, no telomerase mTR was detectable. Type A spermatogonia expressed the highest level of telomerase mTR mRNA. It was suggested that the expression of mTR gene in the testis of SD rats is of lifetime and coincides with the telomerase activity.

Keywords

telomerase / in situ hybridization / germ cell / gene expression

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Fan Min, Chen Xiaochun, Ye Zhewei, Xiong Yali, Zeng Fuqing, Lu Gongcheng. Expression of telomerase gene mTR in the testis of SD rats and its significance. Current Medical Science, 2003, 23(23): 173-175 DOI:10.1007/BF02859948

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