Changes of hepatic function after hepatic artery ligation

Abstract

In our series of 12 patients with unresectable primary liver cancers, hepatic function changes after hepatic artery ligation (HAL) have been investigated. Significant elevation of SGPT, SGOT and LDH were observed on the one hand, and only slight or no derangement in AKP, γ-GT, 5’-NT and bilirubin was noted on the other hand. Factors influencing hepatic function changes after HAL are discussed. The importance of high postoperative oxygen saturation of portal vein blood in maintaining a stable oxygen consumption of hepatocytes is stressed.

Keywords

hepatic function / hepatic artery

References

[1] AlmersjöO, et al. . Serum enzyme change after hepatic dearterialization in man. Ann Surg, 1968, 1679-9

[2] 14: 783, 1981

[3] SparksFC, et al. . Hepatic artery ligation and postoperative pathophysiological results. Cancer, 1975, 351074-1074

[4] NagasueN, et al. . Hepatic dearterialization for nonresectable primary and secondary tumor of the liver. Cancer, 1976, 382593-2593

[5] 2: 79, 1981

[6] KimDK, et al. . Occlusion of the hepatic artery in man. SGO, 1973, 136966-966

[7] TygstrupN, et al. . Determination of the hepatic arterial blood flow and oxygen supply in man by clamping the hepatic artery during surgery. J Clin Invest, 1962, 41447-447