Immunophenotype and ultrastructure of B-cell lymphoproliferative disorder with cytoplasmic projection

Liu Xinyue; Hu Xianshi; Fan Lihua; Yuan Youbing

doi:10.1007/BF02829501

Current Medical Science ›› 2003, Vol. 23 ›› Issue (8) : 236 -238. DOI: 10.1007/BF02829501

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Immunophenotype and ultrastructure of B-cell lymphoproliferative disorder with cytoplasmic projection

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Abstract

To identify the knowledge of rare lymphoproliferative disorder, the clinical and biological features of three kinds of lymphoproliferative disorders with cytoplasmic projections were compared. The clinical manifestations, ultrastructure and immunophenotype were analyzed. The results showed that hairy cell leukemia (HCL), splenic lymphoma with villous lymphocyte (SLVL) and hairy cell leukemia-variant (HCL-V) had some common characters including splenomegaly, peripheral blood and bone marrow infiltration by villous lymphocyte and B lymphocyte immunophenotype; but these three disorders had specific features respectively. It was concluded that overall analysis of clinical and laboratory features might be contributive to the differential diagnosis of these three disorders.

Keywords

lymphoproliferative disorder / hairy cell / immunophenotyping / electron microscopy

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Liu Xinyue, Hu Xianshi, Fan Lihua, Yuan Youbing. Immunophenotype and ultrastructure of B-cell lymphoproliferative disorder with cytoplasmic projection. Current Medical Science, 2003, 23(8): 236-238 DOI:10.1007/BF02829501

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