Diagnostic performance of a circulating tumor DNA-based blood test compared to fecal immunochemical test in colorectal cancer screening

Hermann Brenner; Teresa Seum; Megha Bhardwaj; Michael Hoffmeister

doi:10.1002/cac2.70066

Cancer Communications ›› 2025, Vol. 45 ›› Issue (11) :1496 -1499. DOI: 10.1002/cac2.70066

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Diagnostic performance of a circulating tumor DNA-based blood test compared to fecal immunochemical test in colorectal cancer screening

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Hermann Brenner, Teresa Seum, Megha Bhardwaj, Michael Hoffmeister. Diagnostic performance of a circulating tumor DNA-based blood test compared to fecal immunochemical test in colorectal cancer screening. Cancer Communications, 2025, 45(11): 1496-1499 DOI:10.1002/cac2.70066

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References

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[2]	Cardoso R, Guo F, Heisser T, Hackl M, Ihle P, De Schutter H, et al. Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: an international population-based study. Lancet Oncol. 2021; 22(7):1002-1013.

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[5]	Ola I, Cardoso R, Hoffmeister M, Brenner H. Utilization of colorectal cancer screening tests: a systematic review and time trend analysis of nationally representative data. EClinicalMedicine. 2024; 75:102783.

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[7]	Seum T, Hoffmeister M, Brenner H. Cell-free DNA blood-based test compared to fecal immunochemical test for colorectal cancer screening. Cancer Commun (Lond). 2025; 45(8): 987-989.

[8]	Imperiale TF, Porter K, Zella J, Gagrat ZD, Olson MC, Statz S, et al. Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening. N Engl J Med. 2024; 390(11): 984-993.