Rare germline ATM variants predispose to secondary cancer in chronic lymphocytic leukaemia patients

Anna Petrackova; Jirina Manakova; Romana Nesnadna; Zuzana Kubova; Tomas Papajik; Eva Kriegova

doi:10.1002/cac2.70010

Cancer Communications ›› 2025, Vol. 45 ›› Issue (6) : 669 -672. DOI: 10.1002/cac2.70010

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Rare germline ATM variants predispose to secondary cancer in chronic lymphocytic leukaemia patients

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Anna Petrackova, Jirina Manakova, Romana Nesnadna, Zuzana Kubova, Tomas Papajik, Eva Kriegova. Rare germline ATM variants predispose to secondary cancer in chronic lymphocytic leukaemia patients. Cancer Communications, 2025, 45(6): 669-672 DOI:10.1002/cac2.70010

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[1]	Sud A, Chattopadhyay S, Thomsen H, Sundquist K, Sundquist J, Houlston RS, et al. Analysis of 153 115 patients with hematological malignancies refines the spectrum of familial risk. Blood. 2019; 134(12): 960–9.

[2]	van der Straten L, Levin MD, Dinnessen MAW, Visser O, Posthuma EFM, Doorduijn JK, et al. Risk of second primary malignancies in patients with chronic lymphocytic leukemia: a population-based study in the Netherlands, 1989-2019. Blood Cancer J. 2023; 13(1): 15.

[3]	Petrackova A, Savara J, Turcsanyi P, Gajdos P, Papajik T, Kriegova E. Rare germline ATM variants of uncertain significance in chronic lymphocytic leukaemia and other cancers. Br J Haematol. 2022; 199(3): 371–81.

[4]	Skowronska A, Austen B, Powell JE, Weston V, Oscier DG, Dyer MJ, et al. ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele. Haematologica. 2012; 97(1): 142–6.

[5]	Yuille MR, Condie A, Hudson CD, Bradshaw PS, Stone EM, Matutes E, et al. ATM mutations are rare in familial chronic lymphocytic leukemia. Blood. 2002; 100(2): 603–9.

[6]	Bevan S, Catovsky D, Marossy A, Matutes E, Popat S, Antonovic P, et al. Linkage analysis for ATM in familial B cell chronic lymphocytic leukaemia. Leukemia. 1999; 13(10): 1497–500.

[7]	Tiao G, Improgo MR, Kasar S, Poh W, Kamburov A, Landau DA, et al. Rare germline variants in ATM are associated with chronic lymphocytic leukemia. Leukemia. 2017; 31(10): 2244–7.

[8]	Lampson BL, Gupta A, Tyekucheva S, Mashima K, Petráčková A, Wang Z, et al. Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia. J Clin Oncol. 2023; 41(5): 1116–28.

[9]	Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen WF, et al. Cutting Edge: ATM Influences Germinal Center Integrity. J Immunol. 2019; 202(11): 3137–42.

[10]	Pan-Hammarström Q, Lähdesmäki A, Zhao Y, Du L, Zhao Z, Wen S, et al. Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation. J Exp Med. 2006; 203(1): 99–110.