Efficient 5-ALA-photodynamic therapy in nasopharyngeal carcinoma induces an immunoactivation mediated by tumoral extracellular vesicles and associated with immunogenic cell death

Camille Trioën , Thomas Soulier , Jacquie Massoud , Clément Bouchez , Nicolas Stoup , Anthony Lefebvre , Anne-Sophie Dewalle , Guillaume Paul Grolez , Nadira Delhem , Olivier Moralès

Cancer Communications ›› 2025, Vol. 45 ›› Issue (4) : 401 -405.

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Cancer Communications ›› 2025, Vol. 45 ›› Issue (4) : 401 -405. DOI: 10.1002/cac2.12656
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Efficient 5-ALA-photodynamic therapy in nasopharyngeal carcinoma induces an immunoactivation mediated by tumoral extracellular vesicles and associated with immunogenic cell death

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Camille Trioën, Thomas Soulier, Jacquie Massoud, Clément Bouchez, Nicolas Stoup, Anthony Lefebvre, Anne-Sophie Dewalle, Guillaume Paul Grolez, Nadira Delhem, Olivier Moralès. Efficient 5-ALA-photodynamic therapy in nasopharyngeal carcinoma induces an immunoactivation mediated by tumoral extracellular vesicles and associated with immunogenic cell death. Cancer Communications, 2025, 45(4): 401-405 DOI:10.1002/cac2.12656

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Lefebvre ATC, Renaud S, Laine W, Hennart B, Bouchez C, Leroux B, et al. Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin-9 dependent mechanism. J Extracell Vesicles. 2023; 12(12): e12390.

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2025 The Author(s). Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.

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