SYNCRIP promotes cell cycle progression and lung tumorigenesis by modulating AURKB translation

Hyeon Ji Kim, Hye Guk Ryu, Mingyu Kang, Namgyu Lee, Hyo-Jin Kim, Dahye Lee, Chaeuk Chung, Sangjune Kim, Kyung-Ha Lee, Wanil Kim, Jin-Seok Byun, Kyong-Tai Kim, Do-Yeon Kim

Cancer Communications ›› 2025, Vol. 45 ›› Issue (02) : 138-142.

PDF
Cancer Communications ›› 2025, Vol. 45 ›› Issue (02) : 138-142. DOI: 10.1002/cac2.12634
LETTER TO THE JOURNAL

SYNCRIP promotes cell cycle progression and lung tumorigenesis by modulating AURKB translation

Author information +
History +

Cite this article

Download citation ▾
Hyeon Ji Kim, Hye Guk Ryu, Mingyu Kang, Namgyu Lee, Hyo-Jin Kim, Dahye Lee, Chaeuk Chung, Sangjune Kim, Kyung-Ha Lee, Wanil Kim, Jin-Seok Byun, Kyong-Tai Kim, Do-Yeon Kim. SYNCRIP promotes cell cycle progression and lung tumorigenesis by modulating AURKB translation. Cancer Communications, 2025, 45(02): 138‒142 https://doi.org/10.1002/cac2.12634

References

[1]
Zhivotovsky B, Orrenius S. Cell cycle and cell death in disease: past, present and future. J Intern Med. 2010; 268(5): 395-409.
CrossRef Google scholar
[2]
Borah NA, Reddy MM. Aurora Kinase B Inhibition: A Potential Therapeutic Strategy for Cancer. Molecules. 2021; 26(7): 1981.
CrossRef Google scholar
[3]
Abdul Azeez KR, Chatterjee S, Yu C, Golub TR, Sobott F, Elkins JM. Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP. Nat Commun. 2019; 10(1): 3166.
CrossRef Google scholar
[4]
Song J, Zhou Y, Yakymovych I, Schmidt A, Li C, Heldin CH, et al. The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells. EBioMedicine. 2022; 82: 104155.
CrossRef Google scholar
[5]
Kim DY, Woo KC, Lee KH, Kim TD, Kim KT. hnRNP Q and PTB modulate the circadian oscillation of mouse Rev-erb alpha via IRES-mediated translation. Nucleic Acids Res. 2010; 38(20): 7068-78.
CrossRef Google scholar
[6]
Vasaikar SV, Straub P, Wang J, Zhang B. LinkedOmics: analyzing multi-omics data within and across 32 cancer types. Nucleic Acids Res. 2018; 46(D1): D956-d63.
CrossRef Google scholar
[7]
Chen HH, Yu HI, Chiang WC, Lin YD, Shia BC, Tarn WY. hnRNP Q regulates Cdc42-mediated neuronal morphogenesis. Mol Cell Biol. 2012; 32(12): 2224-38.
CrossRef Google scholar
[8]
Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN. et al. Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells. Nat Genet. 2017; 49(6): 866-75.
CrossRef Google scholar
[9]
Li X, Wang Y, Deng S, Zhu G, Wang C, Johnson NA, et al. Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targete. therapy resistance in prostate cancer. Cancer Cell. 2023; 41(8): 1427-49.e12.
CrossRef Google scholar

RIGHTS & PERMISSIONS

2024 2024 The Author(s). Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.
PDF

Accesses

Citations

Detail

Sections
Recommended

/