Targeting IL-17A to manage immunotherapy-induced toxicity in melanoma

Kai Huang

Cancer Communications ›› 2025, Vol. 45 ›› Issue (01) : 56 -57.

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Cancer Communications ›› 2025, Vol. 45 ›› Issue (01) : 56 -57. DOI: 10.1002/cac2.12628
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Targeting IL-17A to manage immunotherapy-induced toxicity in melanoma

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Kai Huang. Targeting IL-17A to manage immunotherapy-induced toxicity in melanoma. Cancer Communications, 2025, 45(01): 56-57 DOI:10.1002/cac2.12628

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References

[1]

Jing Y, Yang J, Johnson DB, Moslehi JJ, Han L. Harnessing big data to characterize immune-related adverse events. Nat Rev Clin Oncol. 2022; 19(4): 269-280.

[2]

Dimitriou F, Cheng PF, Saltari A, Schaper-Gerhardt K. Staeger R, Haunerdinger V, et al. A targetable type III immune response with increase of IL-17A expressing CD4+ T cells is associated with immunotherapy-induced toxicity in melanoma. Nature Cancer. 2024; 5(9): 1390-1408.

[3]

Suijkerbuijk KPM, van Eijs MJM, van Wijk F, Eggermont AMM. Clinical and translational attributes of immune-related adverse events. Nat Cancer. 2024; 5(4): 557-571.

[4]

Reich K, Sullivan J, Arenberger P, Jazayeri S, Mrowietz U, Augustin M, et al. Secukinumab shows high and sustained efficacy in nail psoriasis: 2.5-year results from the randomized placebo-controlled TRANSFIGURE study. Br J Dermatol. 2021; 184(3): 425-436.

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2024 The Author(s). Cancer Communications published by John Wiley & Sons Australia, Ltd on behalf of Sun Yat-sen University Cancer Center.

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