IL2-mediated modulation of small extracellular vesicles secretion and PD-L1 expression: a novel perspective for neutralizing immune suppression within cancer cells

Soojeong Noh; Suyeon Ryu; Dokyung Jung; Sanghee Shin; Inseong Jung; Sung-Min Kang; Christine Seulki Kim; Sung-Jin Choi; Hanchae Cho; Melanie Schwämmle; Youngtae Jeong; Felicitas Bucher; Il-Kyu Choi; Shin Yup Lee; Sin-Hyeog Im; Kyungmoo Yea; Moon-Chang Baek

doi:10.1002/cac2.12623

Cancer Communications ›› 2024, Vol. 44 ›› Issue (12) : 1422 -1426. DOI: 10.1002/cac2.12623

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IL2-mediated modulation of small extracellular vesicles secretion and PD-L1 expression: a novel perspective for neutralizing immune suppression within cancer cells

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¹. Department of New Biology, DGIST, Daegu, Republic of Korea

². Department of Molecular Medicine, Cell and Matrix Research Institute (CMRI), School of Medicine, Kyungpook National University, Daegu, Republic of Korea

³. Department of Molecular Medicine, Kyungpook National University, Daegu, Republic of Korea

⁴. Faculty of Biology, University of Freiburg, Freiburg im Breisgau, Germany

⁵. Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany

⁶. New Biology Research Center, DGIST, Daegu, Republic of Korea

⁷. Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea

⁸. Lung Cancer Center, Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea

⁹. Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea

ykm31@dgist.ac.kr

mcbaek@knu.ac.kr

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Soojeong Noh, Suyeon Ryu, Dokyung Jung, Sanghee Shin, Inseong Jung, Sung-Min Kang, Christine Seulki Kim, Sung-Jin Choi, Hanchae Cho, Melanie Schwämmle, Youngtae Jeong, Felicitas Bucher, Il-Kyu Choi, Shin Yup Lee, Sin-Hyeog Im, Kyungmoo Yea, Moon-Chang Baek. IL2-mediated modulation of small extracellular vesicles secretion and PD-L1 expression: a novel perspective for neutralizing immune suppression within cancer cells. Cancer Communications, 2024, 44(12): 1422-1426 DOI:10.1002/cac2.12623

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