Interleukin-10 gives exhausted chimeric antigen receptor (CAR) T cells a second breath

Christoph Heuser-Loy

Cancer Communications ›› 2024, Vol. 44 ›› Issue (07) : 787 -790.

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Cancer Communications ›› 2024, Vol. 44 ›› Issue (07) : 787 -790. DOI: 10.1002/cac2.12575
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Interleukin-10 gives exhausted chimeric antigen receptor (CAR) T cells a second breath

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Christoph Heuser-Loy. Interleukin-10 gives exhausted chimeric antigen receptor (CAR) T cells a second breath. Cancer Communications, 2024, 44(07): 787-790 DOI:10.1002/cac2.12575

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Guo Y, Xie YQ, Gao M, Zhao Y, Franco F, Wenes M, et al. Metabolic reprogramming of terminally exhausted CD8(+) T cells by IL-10 enhances anti-tumor immunity. Nat Immunol. 2021; 22(6): 746-56.

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2024 The Author(s). Cancer Communications published by John Wiley & Sons Australia, Ltd on behalf of Sun Yat-sen University Cancer Center.

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