Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy

Andrés Pastor-Fernández, Manuel Montero Gómez de las Heras, Jose Ignacio Escrig-Larena, Marta Barradas, Cristina Pantoja, Adrian Plaza, Jose Luis Lopez-Aceituno, Esther Durán, Alejo Efeyan, Maria Mittelbrunn, Lola Martinez, Pablo Jose Fernandez-Marcos

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Cancer Communications ›› 2024, Vol. 44 ›› Issue (4) : 508-513. DOI: 10.1002/cac2.12535
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Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy

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Andrés Pastor-Fernández, Manuel Montero Gómez de las Heras, Jose Ignacio Escrig-Larena, Marta Barradas, Cristina Pantoja, Adrian Plaza, Jose Luis Lopez-Aceituno, Esther Durán, Alejo Efeyan, Maria Mittelbrunn, Lola Martinez, Pablo Jose Fernandez-Marcos. Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy. Cancer Communications, 2024, 44(4): 508‒513 https://doi.org/10.1002/cac2.12535

References

[1]
Barradas M, Plaza A, Colmenarejo G, Lázaro I, Costa-Machado LF, Martín-Hernández R, et al. Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity. Nat Commun. 2022;13(1):5677.
[2]
Pietrocola F, Pol J, Vacchelli E, Rao S, Enot DP, Baracco EE, et al. Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. Cancer Cell. 2016;30(1):147-60
[3]
Di Biase S, Lee C, Brandhorst S, Manes B, Buono R, Cheng CW, et al. Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity. Cancer Cell. 2016;30(1):136-46.
[4]
Ajona D, Ortiz-Espinosa S, Lozano T, Exposito F, Calvo A, Valencia K, et al. Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade. Nat Cancer. 2020;1(1):75-85.
[5]
Hiramoto K, Homma T, Jikumaru M, Miyashita H, Sato EF, Inoue M. Fasting Differentially Modulates the Immunological System: Its Mechanism and Sex Difference. J Clin Biochem Nutr. 2008;43(2):75-81.
[6]
Jensen TL, Kiersgaard MK, Sørensen DB, Mikkelsen LF. Fasting of mice: a review. Lab Anim. 2013;47(4):225-40.
[7]
Chan JL, Heist K, DePaoli AM, Veldhuis JD, Mantzoros CS. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. Eur J Clin Invest. 2003;111(9):1409.
[8]
Plaza A, Pastor-Fernández A, López-Aceituno JL, Barradas M, Pantoja C, Fernandez-Marcos PJ. p21 is necessary for the beneficial effects of fasting during chemotherapy. Cancer Commun. (London, England). 2023;43(1):164-68.
[9]
Vinay DS, Kwon BS. CD11c+CD8+ T cells: Two-faced adaptive immune regulators. Cell Immunol. 2010;264(1):18-22.
[10]
Vernieri C, Fuca G, Ligorio F, Huber V, Vingiani A, Iannelli F, et al. Fasting-mimicking diet is safe and reshapes metabolism and antitumor immunity in cancer patients. Cancer Discov. 2022;12(1):90-107.

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2024 2024 The Authors. Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.
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