Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

Kouya Shiraishi; Atsushi Takahashi; Yukihide Momozawa; Yataro Daigo; Syuzo Kaneko; Takahisa Kawaguchi; Hideo Kunitoh; Shingo Matsumoto; Hidehito Horinouchi; Akiteru Goto; Takayuki Honda; Kimihiro Shimizu; Masahiro Torasawa; Daisuke Takayanagi; Motonobu Saito; Akira Saito; Yuichiro Ohe; Shun-ichi Watanabe; Koichi Goto; Masahiro Tsuboi; Katsuya Tsuchihara; Sadaaki Takata; Tomomi Aoi; Atsushi Takano; Masashi Kobayashi; Yohei Miyagi; Kazumi Tanaka; Hiroyuki Suzuki; Daichi Maeda; Takumi Yamaura; Maiko Matsuda; Yoko Shimada; Takaaki Mizuno; Hiromi Sakamoto; Teruhiko Yoshida; Yasushi Goto; Tatsuya Yoshida; Taiki Yamaji; Makoto Sonobe; Shinichi Toyooka; Kazue Yoneda; Katsuhiro Masago; Fumihiro Tanaka; Megumi Hara; Nobuo Fuse; Satoshi S. Nishizuka; Noriko Motoi; Norie Sawada; Yuichiro Nishida; Kazuki Kumada; Kenji Takeuchi; Kozo Tanno; Yasushi Yatabe; Kuniko Sunami; Tomoyuki Hishida; Yasunari Miyazaki; Hidemi Ito; Mitsuhiro Amemiya; Hirohiko Totsuka; Haruhiko Nakayama; Tomoyuki Yokose; Kazuyoshi Ishigaki; Toshiteru Nagashima; Yoichi Ohtaki; Kazuhiro Imai; Ken Takasawa; Yoshihiro Minamiya; Kazuma Kobayashi; Kenichi Okubo; Kenji Wakai; Atsushi Shimizu; Masayuki Yamamoto; Motoki Iwasaki; Koichi Matsuda; Johji Inazawa; Yuichi Shiraishi; Hiroyoshi Nishikawa; Yoshinori Murakami; Michiaki Kubo; Fumihiko Matsuda; Yoichiro Kamatani; Ryuji Hamamoto; Keitaro Matsuo; Takashi Kohno

doi:10.1002/cac2.12498

Cancer Communications ›› 2024, Vol. 44 ›› Issue (2) : 287-293. DOI: 10.1002/cac2.12498

LETTER TO THE EDITOR

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

Author information +

¹. Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan

². Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan

³. Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan

⁴. Department of Genomic Medicine, Research Institute, National Cerebral and Cardiovascular Center, Osaka, Japan

⁵. Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan

⁶. Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

⁷. Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Otsu, Japan

⁸. Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan

⁹. Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

¹⁰. Department of Medical Oncology, Japanese Red Cross Medical Center, Tokyo, Japan

¹¹. Department of Thoracic Oncology, National Cancer Center Hospital East, Japan

¹². Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan

¹³. Department of Cellular and Organ Pathology, Graduate School of Medicine, Akita University, Akita, Japan

¹⁴. Department of Respiratory Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

¹⁵. Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan

¹⁶. Department of General Surgical Science, Division of General Thoracic Surgery, Gunma University Graduate School of Medicine, Integrative Center of General Surgery, Gunma University Hospital, Gunma, Japan

¹⁷. Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan

¹⁸. StaGen Co., Ltd, Tokyo, Japan

¹⁹. Division of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan

²⁰. Department of Thoracic Surgery, National Cancer Center Hospital East, Chiba, Japan

²¹. Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Chiba, Japan

²². Department of Thoracic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

²³. Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Kanagawa, Japan

²⁴. Department of Chest Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan

²⁵. Fundamental Innovative Oncology Core Center, National Cancer Center Research Institute, Tokyo, Japan

²⁶. Department of Genetic Medicine and Services, National Cancer Center Hospital, Tokyo, Japan

²⁷. Division of Epidemiology, National Cancer Center Institute for Cancer Control, Tokyo, Japan

²⁸. Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan

²⁹. Departments of General Thoracic Surgery and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

³⁰. Second Department of Surgery, University of Occupational and Environmental Health, Kitakyushu, Japan

³¹. Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan

³². Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan

³³. Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan

³⁴. Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan

³⁵. Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan

³⁶. Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan

³⁷. Division of Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Tokyo, Japan

³⁸. Division of Cancer Information and Control, Aichi Cancer Center Research Institute, Nagoya, Japan

³⁹. Department of Thoracic Surgery, Kanagawa Cancer Center, Kanagawa, Japan

⁴⁰. Department of Pathology, Kanagawa Cancer Center, Yokohama, Japan

⁴¹. Department of Thoracic Surgery, Graduate School of Medicine, Akita University, Akita, Japan

⁴². Division of Cohort Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan

⁴³. Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Science, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan

⁴⁴. Department of Molecular Cytogenetics, Medical Research Institute and Bioresource Research Center, Tokyo Medical and Dental University, Tokyo, Japan

⁴⁵. Division of Genome Analysis Platform Development, National Cancer Center Research Institute, Tokyo, Japan

⁴⁶. Division of Cancer Immunology, Research Institute, National Cancer Center, Tokyo, Japan

⁴⁷. Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

⁴⁸. Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan

kshirais@ncc.go.jp

fumi@genome.med.kyoto-u.ac.jp

yoichiro.kamatani@riken.jp

rhamamot@ncc.go.jp

kmatsuo@aichi-cc.jp

tkkohno@ncc.go.jp

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Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, Yataro Daigo, Syuzo Kaneko, Takahisa Kawaguchi, Hideo Kunitoh, Shingo Matsumoto, Hidehito Horinouchi, Akiteru Goto, Takayuki Honda, Kimihiro Shimizu, Masahiro Torasawa, Daisuke Takayanagi, Motonobu Saito, Akira Saito, Yuichiro Ohe, Shun-ichi Watanabe, Koichi Goto, Masahiro Tsuboi, Katsuya Tsuchihara, Sadaaki Takata, Tomomi Aoi, Atsushi Takano, Masashi Kobayashi, Yohei Miyagi, Kazumi Tanaka, Hiroyuki Suzuki, Daichi Maeda, Takumi Yamaura, Maiko Matsuda, Yoko Shimada, Takaaki Mizuno, Hiromi Sakamoto, Teruhiko Yoshida, Yasushi Goto, Tatsuya Yoshida, Taiki Yamaji, Makoto Sonobe, Shinichi Toyooka, Kazue Yoneda, Katsuhiro Masago, Fumihiro Tanaka, Megumi Hara, Nobuo Fuse, Satoshi S. Nishizuka, Noriko Motoi, Norie Sawada, Yuichiro Nishida, Kazuki Kumada, Kenji Takeuchi, Kozo Tanno, Yasushi Yatabe, Kuniko Sunami, Tomoyuki Hishida, Yasunari Miyazaki, Hidemi Ito, Mitsuhiro Amemiya, Hirohiko Totsuka, Haruhiko Nakayama, Tomoyuki Yokose, Kazuyoshi Ishigaki, Toshiteru Nagashima, Yoichi Ohtaki, Kazuhiro Imai, Ken Takasawa, Yoshihiro Minamiya, Kazuma Kobayashi, Kenichi Okubo, Kenji Wakai, Atsushi Shimizu, Masayuki Yamamoto, Motoki Iwasaki, Koichi Matsuda, Johji Inazawa, Yuichi Shiraishi, Hiroyoshi Nishikawa, Yoshinori Murakami, Michiaki Kubo, Fumihiko Matsuda, Yoichiro Kamatani, Ryuji Hamamoto, Keitaro Matsuo, Takashi Kohno. Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses. Cancer Communications, 2024, 44(2): 287‒293 https://doi.org/10.1002/cac2.12498

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