Progress and mechanism of breaking glycoconjugates by glycosidases in skin for promoting unhairing and fiber opening-up in leather manufacture. A review

Fengxiang Luo , Xiang Zhong , Mengchu Gao , Biyu Peng , Zhongzhen Long

Collagen and Leather ›› 2020, Vol. 2 ›› Issue (1)

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Collagen and Leather ›› 2020, Vol. 2 ›› Issue (1) DOI: 10.1186/s42825-020-00025-0
Review

Progress and mechanism of breaking glycoconjugates by glycosidases in skin for promoting unhairing and fiber opening-up in leather manufacture. A review

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Abstract

The glycoconjugates, herein glyco-proteins, existing in animal skins are closely related to the effectiveness of unhairing and fiber opening-up. Glycosidases have been used in leather making processes to reduce pollutants and improve leather quality. But the selection of glycosidases is still blind because the related mechanisms are not well understood yet. Hence, the animal skin structures and glycoconjugates components, the advances in the methods and mechanisms of removing glycoconjugates related to unhairing and fiber opening-up in leather manufacture, the kinds, compositions, structures and functions of typical glycoconjugates in skin are summarized. Then the approaches to destroy them, possible glycosidases suitable for leather making and their acting sites are analyzed based on the recognition of glycoconjugates in skin and the specificities of glycosidases toward substrates. It is expected to provide useful information for the optimization of glycosidases and the development of new enzymes and the cleaner technologies of unhairing and opening up fiber bundles assisted by glycosidases.

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Fengxiang Luo, Xiang Zhong, Mengchu Gao, Biyu Peng, Zhongzhen Long. Progress and mechanism of breaking glycoconjugates by glycosidases in skin for promoting unhairing and fiber opening-up in leather manufacture. A review. Collagen and Leather, 2020, 2(1): DOI:10.1186/s42825-020-00025-0

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National Key R&D Program of China(2017YFB0308402)

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