Interstitial laser photocoagulation is an advanced minimally invasive treatment for primary hyperparathyroidism. The basis of its use is accurate topical diagnosis changed parathyroid glands (OSCHZH). Proposed fine-needle aspiration biopsy OSCHZH modified with a certain level of parathyroid hormone (PTH) in the wash of the needle (FNAB / PTH). The method is reliable, informative and safe. It is shown that TAPB / PTH allows an accurate verification of modified OSCHZH thereby ensure that minimally invasive treatment of primary hyperparathyroidism without traditional surgery.

In this work, the authors give a theoretical substantiation thyroid resection elderly patients with thyroid disease. Also tell about their own experience of operations on the thyroid gland. In the work has distans results of treatment which were analyzed 120 patients who operated 5 years ago owing to nodular goiter in volume terms: resection, subtotalthyroidectomy, hemithyroidectomy and totalthyroidectomy. Euthyroidism was observed only in the group resection in 48% and subto-talthyroidectomy in 17,2%. In hypothyroidism and compensation was difflcaet due to accompanying pathology of the cardiovascular system.

This article describes the results of research of an umbilical ring biomechanics in patients with umbilical hernia of the small and medium sizes. During work constancy of its form and the sizes is established that, according to the authors, pathogenetic justified of the use of prosthetic techniques. Proposed and developed by authors the method of intraumbilical preperitoneal prosthetics for surgical treatment of patients with this pathologies.

The article provides an overview of world literature data on existing techniques to improve the results of distal reconstructions by applying arteriovenous fistulas in the formation of the distal anastomosis in patients with obliterating diseases of the lower extremities. The data on the benefits of worldwide research of a method depending on the type, shape and location of venous cuffs or patches. Examined the immediate and long-term outcomes with the use of these techniques, data analysis, comparative application autovenous grafts, shunts combined with the use of arteriovenous fistulas in the formation of distal anastomosis and PTFE prostheses in position below the gap of the knee.

In the work we presented the indicators usage of the the organism functional reserves for the objective estimation of the clinical functional conditions peculiarities and the results of patients treatment with lumbar osteochondrosis at the level of sanatorium-and-spa treatment. 120 patients were involved into the investigation. We proved that usage of “Detensor”- therapy improves the results of the complex sanatorium-and-spa treatment of the given category of patients. It allows achieving quicker regress of clinical manifestations of the disease and more expressed increase of the functional reserves of the organism.

In the surgical department of the Central Research Institute of Tuberculosis 226 patients with advanced destructive pulmonary tuberculosis were performed 230 lobectomy resection volume and more. In the main group - (126 patients), 130 was performed using surgical interventions Videoassisted art, in the comparison group - (100 patients), 100 resections were performed by standard methods. When using Watsu art intraoperative blood loss was 2.8 times lower transfusion missing, narcotic analgesics were not used in 80% of cases of postoperative complications was 2.7 times less mortality was absent, and the effectiveness of treatment was higher.

There are data about cancer mortality and morbidity in the population of Ryazan region. Rating of administrative territories allowed to detect deprived territories. There is analysis of risk factors affecting the mortality, morbidity and rate of oncopathology in Ryazan region. It was detected that imbalance of feedstuff, overweight, age, low average income of the population help for prevalence of oncological diseases. Influence of the neglected oncological diseases on mortality and lethality within the first year upon diagnosis of the disease was detected.

The article presents a comparative analysis of the efficiency of allogeneic progenitor cells with different biological carriers for preparation of extensive traumatic wounds to autodermoplasty. As carriers were selected dermal matrix and collagen first type of human. The article presents the results of treatment of 43 patients. Based on these data the effectiveness of the combination of allogeneic progenitor cells and dermal matrix is demonstrated. This combination reduces the incidence of purulent complications and reduce the time of prepare wounds for autodermoplasty.

The efficacy analysis of patient management in inflammatory bowel diseases is provided in the article. The most frequent mistakes in medicament prescription are reviewed. The data are shown on prevalence and management of anemia in this group of patients. The information is given on quality of life in patients with inflammatory bowel diseases and it's connection with the characteristics of the diseases course.

Our experience in use of biologic implant Permacol is shown in the article. An experiment on rabbits was made to compare biologic characteristics of implants Prolen and Permacol, in the result of which Permacol proved good biocompatibility and high resistance to tissular enzymes and infection. In the faculty surgery clinic based on the coloproctological department of Ryazan Regional Clinical Hospital Permacol was used twice: for replacement of anterior abdominal wall defect and for replacement of pelvic floor defect after extended operations on oncological patients. Both cases we had good results. Our experience allows to recommend use of Permacol not in open wound, but cover the prosthesis with skin.

In the work the experimental research of features of dynamics of a complex biochemical parameters of erythrocytes on laboratory animals with a modelled acute hypoxic hypoxia after application of preparation from biomass of ginseng is conducted. Experiments were carried out on rats with acute hypoxic hypoxia which was modelled in a pressure chamber. The statistical analysis of changes of biochemical parameters testifies about rather expressed antihypoxic effect of a preparation from biomass of ginseng.

Polysaccharide complex is excreted from great nettle, qualitative and quantitative monosaccharide composition is determined, its influence on physical activity, processes of phagocytosis, osmotic, thermic and peroxide resistance of erythrocyte membranes is studied.

The article presents data on the number and nature of perioperative complications in 67 patients undergoing hip replacement. 18% of patients had gastro- and duodenopathy; venous system pathology in 21% and chronic DIC in 46%.

The analysis of umbilical cord blood of 174 healthy newborns and 152 small-for-date newborns from different ecological districts of Ivano-Frankovsk region has been performed in order to evaluate the rate of associations of acrocentric chromosomes in neonates from Precarpathian Ukraine. The rate of associations of acrocentric chromosomes in newborns with intra-uterine growth retardation syndrome from the investigated ecological zones was 3,91; 3,0 and 2,07% higher than in healthy newborns from zones of ecological comfort, chemically polluted territories and zones of radiation contamination consequently. The analysis of the average number of associations of acrocentric chromosomes within one cell showed the tendency to the increase of the actual rate in small-for-date newborns from all the investigated zones as compared to its rate in healthy newborns.

The analysis of anthropometric and functional indices 292 male medical students of Voronezh city at the age of 17-21 years was carried out, depending on somatic sexual differentiation. The indexed evaluation of physical development has been received. Most of the boys had a gynaecomorphic or mesomorphic body type. Gynaecomorphism is characterized by a narrow rib cage, increasing of the transverse diameter of the large pelvis, brahiskelia and normoskelia. That is why among gynaecomorphic boys people with strong sexual constitution revealed more significantly. This makes it possible to consider gynaecomorphia in men a predictor of premature aging. Andromorphism is characterized by the ongoing process of acceleration: increasing the length of the body while standing and sitting and trochanter height. Evaluation of physical development of young men showed that the index of sexual dimorphism can be used as a marker in the evaluation of physical health.

The article is devoted to study change of cytomorphometric indicators of gum’s mucous membrane of a dabs prints before and in various terms after treatment hypertrophic gingivitis, edematous form, ortofen and dioksidin ointments.

Basing on the analysis of a registry study, of the usage of diagnostic methods in patients with coronary heart disease in the outPatient setting, and their comPliance with the guidelines of the Russian Society of Cardiology were assessed. An outpatient registry included 3672 patients with hypertension, coronary heart disease, heart failure and atrial fibrillation who aPPealed to theraPist or cardiologist for medical aid. High incidence rate of CHD with hypertension (98.9 %) and CHF (91.3 %) was registered in the study. The registry revealed lack of active CHD patients follow-up by therapists and cardiologists, insufficient use of instrumental and laboratory diagnostic techniques for the confirmation of coronary artery disease.

During the health care reform in various literary sources have different opinions organization of medical care and its impact on key health indicators in different periods of the historical development of our state. A number of publications, go to the organization of primary health care on the basis of a family doctor, compared with the period of zemstvo medicine, while comparing both positive and critical. The aim of healthcare reform in different historical periods of mankind, it is primarily the adoption of such a model, the organization of medical care that would improve access to health care and a positive effect on key health indicators and demographic situation.

On laboratory animals we investigate endothelio- and cardioprotective effects of enalapril, lozartan and amlodipine at modeling hyperhomocystein induced endothelial dysfunction. It is established that use of ACE inhibitors, blockers of ATI of receptors and calcium channels blockers at the general, expressed endothelio-and cardioprotective action, allows to correct only a number of indicators of functioning an vascular endothelium and cardiovascular system as a whole.

The results of the study of morphological and functional parameters of the heart, gene polymorphism AGT (T174M), TNF-Α (G308A) and MTHFR (A222V) in patients after Q-myocardial infarction with chronic heart failure, II, III functional class. In patients undergoing Q- myocardial infarction adverse clinical phenotype of chronic heart failure is associated with alleles and genotypes T/M, M/M gene AGT (T174M), and A allele genotypes A/G, A/A gene TNF-α (G-308A), C allele and genotype C/T gene MTHFR (A222V).

Lipid peroxidation (LPO), antioxidant system (AOS), of patients with acne without concomitant diseases and disorders of the digestive system during treatment with using of bee products were studied. Patients with acne increased free radical activity on the background of oppression antioxidant defense deteriorated, but in patients with disorders of the gastrointestinal tract the data correlates were more expressed. The processes were stabilized after the using into the complex therapy of bee products.

The subjects of the electronic microscopy exploration are the phases of human liver and spleen blood capillary formation during the early stages of pregnancy under the effect of the anthropogenic on hepatic and splenic cell euchromatin of embryos and fetuses disturbances of angio-genesis identified.

The subject of the article is a study of systemic organization of purposeful behavior of a human in reproduction of visual images. Exposure time of visual images and role of feedback in purposeful behavior of different degree of successfulness are studied in test objects. On the basis of variability of the cardiac rhythm, a different degree of correlation relationships between characteristics of reproduction of visual images and parameters of “physiologic value” of the activity is demonstrated in individuals with different degree of successfulness of the activity.

The 180 school-children 8-9 years age-old from Meleuz and Meleuz district of Bashkortostan Republic (53 0 north breadth) in autumn (September) were investigated the content of 25-hydroxyvitamin D, parathyroid hormone, calcium, phosphorus, magnesium in the serum and the level of daily intake of calcium from food. As a result of data analysis was concluded that 72% of the urban and 29,6% of rural children have a deficiency of vitamin D, with 28% and 63% respectively D-subclinical vitamin deficiency. Parathyroid hormone content was higher in of urban children than in rural areas. Daily calcium intake was 60-70% age norms and does not significantly differ from place of residence. The amount of milk and dairy products consumed by children is significantly lower than the recommended norms and is 26-39%.

Mechanisms of synchronization effect of magnetic waves to the regulation mechanisms are discussed in the article. By means of cardiointervalomethric method, an adaptation of a whole organism to the different combinations of wave parameters is described. Synchronization- and desynchronization-realising combinations of stimulus parameters are released, which increase vasomotor regulation activities; correlation between synchronization of neural centers activities and stress-index are described.

The research of morphological changes in a wall of the main arteries at the patients were operated about restenosis or reocclusion, after earlier executed reconstructive interventions on an aorto-femoral segment, have been conducted. It have been revealed that performance of an endarterectomy leads to rough damage of the vascular wall with formation of neointimus changes and cicatrization. Implantation to a vascular wall a foreign matter leads to develop the chronic productive inflammation, being accompanied the excess growth of textus connectivus. The revealed changes significantly differ from those at atherosclerotic defeat.