Please wait a minute...

Frontiers of Medicine

Front. Med.    2020, Vol. 14 Issue (5) : 681-688     https://doi.org/10.1007/s11684-020-0801-x
COMMENTARY
The role played by traditional Chinese medicine in preventing and treating COVID-19 in China
Qingwei Li1, Han Wang1,2, Xiuyang Li1, Yujiao Zheng1,3, Yu Wei1,3, Pei Zhang1, Qiyou Ding1,3, Jiaran Lin1,4, Shuang Tang1,4, Yikun Zhao5, Linhua Zhao1(), Xiaolin Tong1()
1. Department of Endocrinology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100056, China
2. Academic Inheritance Workstation of Academician Tong Xiaolin of Shenzhen Hospital of Guangzhou University of Traditional Chinese Medicine, Shenzhen 518034, China
3. Beijing University of Chinese Medicine, Beijing 100019, China
4. Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
5. Gansu University of Chinese Medicine, Lanzhou 730000, China
Download: PDF(120 KB)   HTML
Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks
Abstract

Traditional Chinese medicine (TCM), an ancient system of alternative medicine, played an active role in the prevention and control of COVID-19 in China. It improved the clinical symptoms of patients, reduced the mortality rate, improved the recovery rate, and effectively relieved the operating pressure on the national medical system during critical conditions. In light of the current global pandemic, TCM-related measures might open up a new channel in the control of COVID-19 in other countries and regions. Here, we summarize the TCM-related measures that were widely used in China, including TCM guidelines, the Wuchang pattern, mobile cabin hospitals, integrated treatment of TCM and modern medicine for critical patients, and non-medicine therapy for convalescent patients, and describe how TCM effectively treated patients afflicted with the COVID-19. Effective TCM therapies could, therefore, be recommended and practiced based on the existing medical evidence from increased scientific studies.

Keywords traditional Chinese medicine      COVID-19      Wuchang pattern      mobile cabin hospital      convalescent patients      three formulae and three medicines     
Corresponding Author(s): Linhua Zhao,Xiaolin Tong   
Just Accepted Date: 09 June 2020   Online First Date: 10 July 2020    Issue Date: 12 October 2020
 Cite this article:   
Qingwei Li,Han Wang,Xiuyang Li, et al. The role played by traditional Chinese medicine in preventing and treating COVID-19 in China[J]. Front. Med., 2020, 14(5): 681-688.
 URL:  
http://journal.hep.com.cn/fmd/EN/10.1007/s11684-020-0801-x
http://journal.hep.com.cn/fmd/EN/Y2020/V14/I5/681
Service
E-mail this article
E-mail Alert
RSS
Articles by authors
Qingwei Li
Han Wang
Xiuyang Li
Yujiao Zheng
Yu Wei
Pei Zhang
Qiyou Ding
Jiaran Lin
Shuang Tang
Yikun Zhao
Linhua Zhao
Xiaolin Tong
1 World Health Organization. Coronavirus disease (COVID-19) situation report–128. 2020. (accessed May 28, 2020)
2 National Health Commission of the People’s Republic of China. The latest situation of the COVID-19 situation as of 24:00 on March 29. 2020. (in Chinese) (accessed May 28, 2020)
3 People’s Daily. “Three formulas and three medicines” selected as COVID-19 treatment and over 90% of patients were applied to the TCM treatment. 2020.(in Chinese) (accessed May 28, 2020)
4 World Health Organization. ICD-11: Classifying disease to map the way we live and die. 2018.
5 Z Wu, JM McGoogan. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020; 323(13): 1239
https://doi.org/10.1001/jama.2020.2648 pmid: 32091533
6 P Song, L Zhao, X Li, J Su, Z Jiang, B Song, W Liu, S Tang, Y Lei, Q Ding, Z Yang, J Lin, Y Wei, X Tong. Interpretation of TCM part in Diagnosis and Treatment Protocol for COVID-19 (Trial Version 7). J Tradit Chin Med 2020; [Epub ahead of print] (accessed May 28, 2020)
7 National Administration of Traditional Chinese Medicine. Xiaolin Tong: “Wuchang pattern” with Chinese medicine characteristics provided new ideas for community prevention and control of COVID-19. 2020. (in Chinese) (accessed May 28, 2020)
8 BL Zhang. What role has traditional Chinese medicine played in the prevention and treatment of COVID-19. Study Times (Xue Xi Shi Bao) 2020-3-18. 6 (in Chinese)
9 H Wang. Analysis of curative effect of Reduning injection on children with lobar pneumonia. Heilongjiang Med Pharm (Heilongjiang Yi Yao Ke Xue) 2019; 42(3): 131–132 (in Chinese)
10 F Bai, D Xu, S Jiang. 40 cases of adult bronchopneumonia treated by Reduning injection. West J Tradit Chin Med (Xi Bu Zhong Yi Yao) 2019; 32(2): 98–100 (in Chinese)
11 Q Yin, JX Zhang, TH Yu, SM Li. Clinical effect of ribavirin injection combined with Tanreqing ultrasonic atomization in treating viral pneumonia caused by influenza virus infection. Chin J Clin Rational Drug Use (Lin Chuang He Li Yong Yao Za Zhi) 2016; 9(12): 10–11,14 (in Chinese)
12 RZ Yuan, H Wang, WH Han, MC Ma, XL Yang. Effect of Tanreqing injection on CRP, PCT, WBC and cellular immune indexes in severe pneumonia. Chin J Diff Cases (Yi Nan Bing Za Zhi) 2016; 15(2): 147–149,153 (in Chinese)
13 S Zhao, Y Liu, F Fan, X Wang, Z Jin, W Wang, XC Da Li. Traditional Chinese medicine treatment strategy for convalescent patients with severe or critical cases of COVID-19. J Hunan Univ Chin Med (Hunan Zhong Yi Yao Da Xue Xue Bao) 2020; 40(4): 387–391 (in Chinese)
14 L Lan, D Xu, G Ye, C Xia, S Wang, Y Li, H Xu. Positive RT-PCR test results in patients recovered from COVID-19. JAMA 2020; 323(15): 1502
https://doi.org/10.1001/jama.2020.2783 pmid: 32105304
15 XD Li, BY Liu, Y Wang, L Guan, GX Li, H, Wang J Wang, CS Weng, MZ Xiao, XL Tong . Interpretation of Recommendation on the Rehabilitation Guidance of Traditional Chinese Medicine for Coronavirus Disease in the Recovery Period (Trial). J Tradit Chin Med (Zhong Yi Za Zhi) 2020; 61(11): 928–934 (in Chinese)
16 Wang JP. TCM anti-epidemic 27: Tong Xiaolin team announced three new research results on COVID-19. 2020. https://www.hubpd.com/c/2020-03-31/954815.shtml?from=timeline&isappinstalled=0
17 K Hu, WJ Guan, Y Bi, W Zhang, L Li, B Zhang, Q Liu, Y Song, X Li, Z Duan, Q Zheng, Z Yang, J Liang, M Han, L Ruan, C Wu, Y Zhang, ZH Jia, NS Zhong. Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: a multicenter, prospective, randomized controlled trial. Phytomedicine 2020; 153242
https://doi.org/10.1016/j.phymed.2020.153242 pmid: 32425361
18 The State Council Information Office of the People’s Republic of China. The State Council Information Office held a conference on the important role of Chinese medicine in the prevention and treatment COVID-19 and related effective drugs. 2020. (in Chinese) (accessed May 28, 2020)
19 KT Yao, MH Liu, X Li, JH Huang, HB Cai. Retrospective clinical analysis of traditional Chinese medicine Lianhua Qingwen granule in treating new coronavirus pneumonia. Chin J Exp Tradit Med Form (Zhongguo Shi Yan Fang Ji Xue Za Zhi) 2020; 26(11): 8–12 (in Chinese)
20 D Cheng, Y Li. Clinical analysis and typical case report of 54 patients with COVID-19 treated by Lianhua Gingwen granule. World Chinese Medicine 2020; 15(2): 150–154
21 DZ Cheng, WJ Wang, Y Li, XD Wu, B Zhou, QY Song. Analysis of the efficacy of Chinese medicine Lianhua Qingwen granule in 51 patients with COVID-19: a multicenter retrospective study. Tianjin J Tradit Chin Med (Tianjin Zhong Yi Yao Za Zhi) 2020; [Epub ahead of print] (in Chinese) (accessed May 28, 2020)
22 RF Li, YL Hou, JC Huang, WQ Pan, QH Ma, YX Shi, CF Li, J Zhao, ZH Jia, HM Jiang, K Zheng, SX Huang, J Dai, XB Li, XT Hou, L Wang, NS Zhong, ZF Yang. Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2). Pharmacol Res 2020; 156: 104761
https://doi.org/10.1016/j.phrs.2020.104761 pmid: 32205232
23 C Duan. WG Xia, CJ Zheng, GB Sun, ZL Li, QL Li, P Li, HL Zhang, FW Yang, BL Zhang, QQ Liu. Clinical observation of Jinhua Qinggan granule in treating COVID-19. J Tradit Chin Med (Zhong Yi Za Zhi) 2020; [Epub ahead of print] (in Chinese) (accessed May 28, 2020)
24 PY Gong, YJ Guo, XP Li, N Wang, J Gu. Research on potential drugs of Jinhua Qinggan granule for preventing and treating COVID-19 based on network pharmacology and pharmacodynamic research. Chin Tradit Herb Drugs (Zhong Cao Yao) 2020; [Epub ahead of print]
25 Y Song, C Yao, Y Yao, H Han, X Zhao, K Yu, L Liu, Y Xu, Z Liu, Q Zhou, Y Wang, Z Ma, Y Zheng, D Wu, Z Tang, M Zhang, S Pan, Y Chai, Y Song, J Zhang, L Pan, Y Liu, H Yu, X Yu, H Zhang, X Wang, Z Du, X Wan, Y Tang, Y Tian, Y Zhu, H Wang, X Yan, Z Liu, B Zhang, N Zhong, H Shang, C Bai. XueBiJing Injection versus placebo for critically ill patients with severe community-acquired pneumonia: a randomized controlled trial. Crit Care Med 2019; 47(9): e735–e743
https://doi.org/10.1097/CCM.0000000000003842 pmid: 31162191
26 National Administration of Traditional Chinese Medicine. Huashi Baidu granule: ancient and innovative wisdom of traditional Chinese medicine. 2020. (in Chinese) (accessed May 28, 2020)
27 National Administration of Traditional Chinese Medicine. Progress in screening research on effective prescriptions of traditional Chinese medicine. 2020. (in Chinese) (accessed May 28, 2020)
28 National Administration of Traditional Chinese Medicine. Qingfei Paidu decoction had good feedback. 2020. (in Chinese) (accessed May 28, 2020)
29 Y Wang, X Li, JH Zhang, R Xue, JY Qian, XH Zhang, H Zhang, QQ Liu, XH Fan, JY Cheng, BL Zhang. Study on the mechanism of Xuanfei Baidu decoction in treating COVID-19 based on network pharmacology. Chin J Chin Materia Medica (Zhongguo Zhong Yao Za Zhi) 2020; 45(10):2249–2256 (in Chinese)
Related articles from Frontiers Journals
[1] Mian Peng, Xueyan Liu, Jinxiu Li, Di Ren, Yongfeng Liu, Xi Meng, Yansi Lyu, Ronglin Chen, Baojun Yu, Weixiong Zhong. Successful management of seven cases of critical COVID-19 with early noninvasive–invasive sequential ventilation algorithm and bundle pharmacotherapy[J]. Front. Med., 2020, 14(5): 674-680.
[2] Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li. Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19[J]. Front. Med., 2020, 14(5): 664-673.
[3] Zhihang Peng, Wenyu Song, Zhongxing Ding, Quanquan Guan, Xu Yang, Qiaoqiao Xu, Xu Wang, Yankai Xia. Linking key intervention timings to rapid declining effective reproduction number to quantify lessons against COVID-19[J]. Front. Med., 2020, 14(5): 623-629.
[4] Chen Xu, Yinqiao Dong, Xiaoyue Yu, Huwen Wang, Lhakpa Tsamlag, Shuxian Zhang, Ruijie Chang, Zezhou Wang, Yuelin Yu, Rusi Long, Ying Wang, Gang Xu, Tian Shen, Suping Wang, Xinxin Zhang, Hui Wang, Yong Cai. Estimation of reproduction numbers of COVID-19 in typical countries and epidemic trends under different prevention and control scenarios[J]. Front. Med., 2020, 14(5): 613-622.
[5] Jiuyang Xu, Chaolin Huang, Guohui Fan, Zhibo Liu, Lianhan Shang, Fei Zhou, Yeming Wang, Jiapei Yu, Luning Yang, Ke Xie, Zhisheng Huang, Lixue Huang, Xiaoying Gu, Hui Li, Yi Zhang, Yimin Wang, Frederick G. Hayden, Peter W. Horby, Bin Cao, Chen Wang. Use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in context of COVID-19 outbreak: a retrospective analysis[J]. Front. Med., 2020, 14(5): 601-612.
[6] Zhengqian Li, Taotao Liu, Ning Yang, Dengyang Han, Xinning Mi, Yue Li, Kaixi Liu, Alain Vuylsteke, Hongbing Xiang, Xiangyang Guo. Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from the periphery to the brain[J]. Front. Med., 2020, 14(5): 533-541.
[7] Cenyi Shao, Shijian Li, Feng Zhu, Dahai Zhao, Hui Shao, Haixiao Chen, Zhiruo Zhang. Taizhou’s COVID-19 prevention and control experience with telemedicine features[J]. Front. Med., 2020, 14(4): 506-510.
[8] Mengxue Huang, Jingjing Wang, Runshun Zhang, Zhuying Ni, Xiaoying Liu, Wenwen Liu, Weilian Kong, Yao Chen, Tiantian Huang, Guihua Li, Dan Wei, Jianzhong Liu, Xuezhong Zhou. Symptom network topological features predict the effectiveness of herbal treatment for pediatric cough[J]. Front. Med., 2020, 14(3): 357-367.
[9] Qiqi Zhao, Xin Gao, Guangli Yan, Aihua Zhang, Hui Sun, Ying Han, Wenxiu Li, Liang Liu, Xijun Wang. Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency syndrome[J]. Front. Med., 2020, 14(3): 335-356.
[10] Guangbiao Zhou, Saijuan Chen, Zhu Chen. Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies[J]. Front. Med., 2020, 14(2): 117-125.
[11] Yong Li, Fan He, Ning Zhou, Jia Wei, Zeyang Ding, Luyun Wang, Peng Chen, Shuiming Guo, Binhao Zhang, Xiaoning Wan, Wei Zhu, on behalf of Multidisciplinary Team for COVID-19, Optical Valley Branch of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Organ function support in patients with coronavirus disease 2019: Tongji experience[J]. Front. Med., 2020, 14(2): 232-248.
[12] Zhiruo Zhang, Shelan Liu, Mi Xiang, Shijian Li, Dahai Zhao, Chaolin Huang, Saijuan Chen. Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions[J]. Front. Med., 2020, 14(2): 229-231.
[13] Fanghua Gong, Yong Xiong, Jian Xiao, Li Lin, Xiaodong Liu, Dezhong Wang, Xiaokun Li. China’s local governments are combating COVID-19 with unprecedented responses ---- from a Wenzhou governance perspective[J]. Front. Med., 2020, 14(2): 220-224.
[14] Shuxian Zhang, Zezhou Wang, Ruijie Chang, Huwen Wang, Chen Xu, Xiaoyue Yu, Lhakpa Tsamlag, Yinqiao Dong, Hui Wang, Yong Cai. COVID-19 containment: China provides important lessons for global response[J]. Front. Med., 2020, 14(2): 215-219.
[15] Ruijie Chang, Huwen Wang, Shuxian Zhang, Zezhou Wang, Yinqiao Dong, Lhakpa Tsamlag, Xiaoyue Yu, Chen Xu, Yuelin Yu, Rusi Long, Ning-Ning Liu, Qiao Chu, Ying Wang, Gang Xu, Tian Shen, Suping Wang, Xiaobei Deng, Jinyan Huang, Xinxin Zhang, Hui Wang, Yong Cai. Phase- and epidemic region-adjusted estimation of the number of coronavirus disease 2019 cases in China[J]. Front. Med., 2020, 14(2): 199-209.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed