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Frontiers of Environmental Science & Engineering

Front. Environ. Sci. Eng.    2015, Vol. 9 Issue (6) : 962-969
Effect of effluent organic matter on ozonation of bezafibrate
Huan HE1,Qian SUI1,3,*(),Shuguang LU1,Wentao ZHAO2,Zhaofu QIU1,Gang YU3
1. State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China
2. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China
3. School of Environment, THU – VEOLIA Joint Research Center for Advanced Environmental Technology, Tsinghua University, Beijing 100084, China
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The influence of three effluent organic matter (EfOM) model compounds, humic acid (HA), bovine serum albumin (BSA), and sodium alginate (AGS), on the ozonation of bezafibrate (BF), a typical pharmaceutical and personal care product (PPCP), was investigated. The results show that ozonation efficiently removed BF from aqueous solution with removal efficiencies>95% within 8 min for all conditions. The reaction rate of BF decreased with increasing model compounds concentrations and the influence was more pronounced for HA and BSA, while less pronounced for AGS. Although BF concentration was significantly reduced, the degree of mineralization achieved was only approximately 11%. The addition of HA and BSA improved the mineralization of the solution, while the influence of AGS was minor. The acute toxicity of BF solution during ozonation was determined using the Luminescent bacteria test, and the toxicity exhibited an initial increase and a successive reduction. An overall decreased acute toxicity was observed with an increase of HA. The presence of BSA increased the formation rate of toxicity intermediates and resulted in inhibition peak forward.

Keywords ozonation      bezafibrate      acute toxicity      humic acid      bovine serum albumin      sodium alginate     
Corresponding Author(s): Qian SUI   
Just Accepted Date: 31 December 2014   Online First Date: 21 January 2015    Issue Date: 23 November 2015
 Cite this article:   
Huan HE,Qian SUI,Shuguang LU, et al. Effect of effluent organic matter on ozonation of bezafibrate[J]. Front. Environ. Sci. Eng., 2015, 9(6): 962-969.
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Huan HE
Qian SUI
Shuguang LU
Wentao ZHAO
Zhaofu QIU
Gang YU
Fig.1  Diagram of ozonation system
Fig.2  Evolution of the concentration of BF (a) and acute toxicity (c), and TOC removal after 25 min (b) during ozonation at different HA concentrations
EfOM TOC/(mg·L−1) kO3 ( × 10−3)/(L·mol−1·s−1) R2
HA 0 10.9±0.67 0.9895
3.0 9.6±0.015 0.9725
7.0 9.2±0.44 0.9655
12.0 7.0±0.13 0.9901
BSA 0 7.0±0.095 0.9856
1.5 5.8±0.13 0.9819
3.0 5.7±0.46 0.9750
6.0 5.4±0.26 0.9667
AGS 0 9.7±0.71 0.9892
0.5 8.8±0.58 0.9979
1.0 8.4±0.18 0.9884
3.0 8.0±0.63 0.9857
Tab.1  Apparent kinetic constants (kO3) of BF ozonation at different EfOM concentrations
solution initial TOC/(mg·L−1) TOC after 25min/(mg·L−1) TOC removal/%
only BF 5.3±0.2 4.7±0.1 11.3±3.2
only HA 12.5±0.4 8.5±0.3 32.1±0.1
only BSA 6.5±0.3 5.4±0.2 16.1±1.5
only AGS 3.2±0.1 2.8±0.1 12.4±2.4
BF+ HA 17.5±0.5 11.0±0.7 37.3±2.3
BF+ BSA 12.7±0.7 7.8±0.6 40.0±2.7
BF+ AGS 8.0±0.1 7.3±0.2 9.4±3.1
Tab.2  Comparison of TOC removal after 25 min of ozonation
Fig.3  Evolution of the concentration of BF (a) and acute toxicity (c), and TOC removal after 25 min (b) during ozonation at different BSA concentrations
Fig.4  Evolution of the concentration of BF (a) and acute toxicity (c), and TOC removal after 25 min (b) during ozonation at different AGS concentrations
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