Multiple functions of SWI/SNF chromatin remodeling complex in plant-pathogen interactions

Abstract

The SWI/SNF chromatin remodeling complex utilizes the energy of ATP hydrolysis to facilitate chromatin access and plays essential roles in DNA-based events. Studies in animals, plants and fungi have uncovered sophisticated regulatory mechanisms of this complex that govern development and various stress responses. In this review, we summarize the composition of SWI/SNF complex in eukaryotes and discuss multiple functions of the SWI/SNF complex in regulating gene transcription, mRNA splicing, and DNA damage response. Our review further highlights the importance of SWI/SNF complex in regulating plant immunity responses and fungal pathogenesis. Finally, the potentials in exploiting chromatin remodeling for management of crop disease are presented.

Keywords

Chromatin remodeling / SWI/SNF complex / Transcription / Splicing / DNA damage repair / Plant-pathogen interaction

References

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Funding

Science and Technology Project of Zhejiang Province(2018C02G2011110); China Postdoctoral Science Foundation(2021M692849); National Natural Science Foundation of China(31930088); China Agriculture Research System of MOF and MARAC(CARS-3-1-29)