Functional materials for bioresorbable medical systems: recent advances and emerging biomedical applications

Hanun Ryu

Soft Science ›› 2026, Vol. 6 ›› Issue (3) : 55

PDF
Soft Science ›› 2026, Vol. 6 ›› Issue (3) :55 DOI: 10.20517/ss.2026.61
Perspective
Functional materials for bioresorbable medical systems: recent advances and emerging biomedical applications
Author information +
History +
PDF

Cite this article

Download citation ▾
Hanun Ryu. Functional materials for bioresorbable medical systems: recent advances and emerging biomedical applications. Soft Science, 2026, 6 (3) : 55 DOI:10.20517/ss.2026.61

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Ryu H,Rogers JA.Bioresorbable metals for biomedical applications: from mechanical components to electronic devices.Adv Healthc Mater2021;10:e2002236

[2]

Park DY,Kim S.Recent advances in bioresorbable biomedical applications: from materials to devices.Adv Elect Materials2025;11:2400997

[3]

Sun H,Robilotto GL.Liquid-based encapsulation for implantable bioelectronics across broad pH environments.Nat Commun2025;16:1019 PMCID:PMC11762702

[4]

Han WB,Yeo W.Recent advances in encapsulation strategies for flexible transient electronics.Flex Print Electron2024;9:033001

[5]

Hawker MJ,Fisher ER.Conformal encapsulation of three-dimensional, bioresorbable polymeric scaffolds using plasma-enhanced chemical vapor deposition.Langmuir2014;30:12328-36

[6]

Zhu Y,Zhou J.Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating.Nat Commun2024;15:1123 PMCID:PMC10847440

[7]

Hong C,Lee T.Optical wireless data transfer through skin for implantable biomedical electronics.npj Flex Electron2025;9:500

[8]

Wan J,Xu J.Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing.Sci Adv2024;10:eadm9314 PMCID:PMC10954204

[9]

Boys AJ,Ma L.Implantable bioelectronics for gut electrophysiology.Nat Commun2025;16:10240 PMCID:PMC12635400

[10]

Yamagishi K,Yokota T.Soft, flexible, and stretchable platforms for tissue-interfaced bioelectronics.Adv Sci2026;13:e21521 PMCID:PMC12956006

[11]

Li Y,Liu W.Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design.Nat Commun2023;14:4488 PMCID:PMC10372055

[12]

Shin Y,Hong YJ.Low-impedance tissue-device interface using homogeneously conductive hydrogels chemically bonded to stretchable bioelectronics.Sci Adv2024;10:eadi7724 PMCID:PMC10954228

[13]

Sun C,Abu-Halimah J.Perspectives on tissue-like bioelectronics for neural modulation.iScience2023;26:106715 PMCID:PMC10192532

[14]

Lee G,Yoon HJ.A bioresorbable peripheral nerve stimulator for electronic pain block.Sci Adv2022;8:eabp9169 PMCID:PMC9534494

[15]

Jiang Y,Sun J.A universal interface for plug-and-play assembly of stretchable devices.Nature2023;614:456-62

[16]

Lee HS,Choi H.Facile and robust integration of functional hydrogels into micropillar-structured elastomer platforms for stable cardiac bioelectronics.Sci Adv2026;12:eaeb9059 PMCID:PMC12757045

[17]

Dobrzyńska-Mizera M,Liu X.Engineering of bioresorbable polymers for tissue engineering and drug delivery applications.Adv Healthc Mater2024;13:e2401674 PMCID:PMC11616265

[18]

Harpaz D,Yitian AL,Marks RS.Dissolvable polyvinyl-alcohol film, a time-barrier to modulate sample flow in a 3D-printed holder for capillary flow paper diagnostics.Materials2019;12:343 PMCID:PMC6384612

[19]

Chaigneau L,Brezulier D,Chevire F.Bioresorbable polylactic acid (PLA) and bioactive glasses (BG) composite: influence of gold coated of BG powder on mechanical properties and chemical reactivity.J Mech Behav Biomed Mater2023;138:105571

[20]

Low YJ,Ang BC.Bioresorbable and degradable behaviors of PGA: current state and future prospects.Polym Eng Sci2020;60:2657-75

[21]

Archer E,Madbouly S.Biodegradable polycaprolactone (PCL) based polymer and composites.Phys Sci Rev2023;8:4391-414

[22]

Basu A.Recent advances in polyanhydride based biomaterials.Adv Mater2018;30:e1706815

[23]

Wan L,Zhu T.Bulk erosion degradation mechanism for poly(1,8-octanediol-co-citrate) elastomer: an in vivo and in vitro investigation.Biomacromolecules2022;23:4268-81

[24]

Tsuji H,Ono T,Daimon H.Hydrolytic degradation and monomer recovery of poly(butylene succinate) and poly(butylene succinate/adipate) in the melt.Macro React Eng2008;2:522-8

[25]

Wang H,Christiansen DE.Thermoplastic polyurethane with controllable degradation and critical anti-fouling properties.Biomater Sci2021;9:1381-96

[26]

Abdalkarim SYH,Song ML,Yao J.In vitro degradation and possible hydrolytic mechanism of PHBV nanocomposites by incorporating cellulose nanocrystal-ZnO nanohybrids.Carbohydr Polym2017;176:38-49

[27]

Salomez M,Fabre P.A comparative study of degradation mechanisms of PHBV and PBSA under laboratory-scale composting conditions.Polym Degrad Stab2019;167:102-13

[28]

Browning MB,Luong PT.Determination of the in vivo degradation mechanism of PEGDA hydrogels.J Biomed Mater Res A2014;102:4244-51 PMCID:PMC4112173

[29]

Wang Y,Sheppard BJ.A tough biodegradable elastomer.Nat Biotechnol2002;20:602-6

[30]

Polak-Kraśna K,Shirazi RN.Physical and mechanical degradation behaviour of semi-crystalline PLLA for bioresorbable stent applications.J Mech Behav Biomed Mater2021;118:104409

[31]

Makadia HK.Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier.Polymers2011;3:1377-97 PMCID:PMC3347861

[32]

Haynes WM. CRC Handbook of chemistry and physics, 97th ed.; CRC Press, 2016. https://books.google.com/books?id=VVezDAAAQBAJ. (accessed 2026-06-03)

[33]

Koo J,Kang SK.Wireless bioresorbable electronic system enables sustained nonpharmacological neuroregenerative therapy.Nat Med2018;24:1830-6

[34]

Hwang SW,Kim DH.A physically transient form of silicon electronics.Science2012;337:1640-4 PMCID:PMC3786576

[35]

Yang Q,Xue Y.Ecoresorbable and bioresorbable microelectromechanical systems.Nat Electron2022;5:526-38

[36]

Kwon K,Won SM.A battery-less wireless implant for the continuous monitoring of vascular pressure, flow rate and temperature.Nat Biomed Eng2023;7:1215-28

[37]

Guo Q,Xie Z.A bioresorbable magnetically coupled system for low‐frequency wireless power transfer.Adv Funct Mater2019;29:1905451

[38]

Yang Q,Yin RT.Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues.Nat Mater2021;20:1559-70 PMCID:PMC8551016

[39]

Liu J,Xu Y.Bioresorbable shape-adaptive structures for ultrasonic monitoring of deep-tissue homeostasis.Science2024;383:1096-103

[40]

Choi YS,Yin RT.A transient, closed-loop network of wireless, body-integrated devices for autonomous electrotherapy.Science2022;376:1006-12 PMCID:PMC9282941

[41]

Lee G,Avila R.Implantable, bioresorbable radio frequency resonant circuits for magnetic resonance imaging.Adv Sci2024;11:e2301232 PMCID:PMC11251549

[42]

Zhang Y,Zeng L.Millimetre-scale bioresorbable optoelectronic systems for electrotherapy.Nature2025;640:77-86 PMCID:PMC13034798

[43]

Reeder JT,Yang Q.Soft, bioresorbable coolers for reversible conduction block of peripheral nerves.Science2022;377:109-15

[44]

Lee DM,Hyun I.An on-demand bioresorbable neurostimulator.Nat Commun2023;14:7315 PMCID:PMC10640647

[45]

Say MG,Cai Y.Bioresorbable RFID capsule for assessing medication adherence.Nat Commun2026;17:52 PMCID:PMC12783801

[46]

Choi YS,Pfenniger A.Fully implantable and bioresorbable cardiac pacemakers without leads or batteries.Nat Biotechnol2021;39:1228-38 PMCID:PMC9270064

[47]

Hehrlein C,Kress N.Zn-alloy provides a novel platform for mechanically stable bioresorbable vascular stents.PLoS One2019;14:e0209111 PMCID:PMC6314592

[48]

Ryu H,Xie Z.Materials and design approaches for a fully bioresorbable, electrically conductive and mechanically compliant cardiac patch technology.Adv Sci2023;10:e2303429 PMCID:PMC10520666

PDF

1

Accesses

0

Citation

Detail

Sections
Recommended

/

〈 〉