Enhancing γ-aminobutyric acid production by Enterococcus faecalis through atmospheric and room temperature plasma mutagenesis, adaptive evolution, and systematic fermentation optimization

Rumeng Han , Kun Qi , Shengming Gu , Qing Ding , Yimei Wang , Min Zhang , Mengkai Hu , Zhenglian Xue , Xiangfei Li

Systems Microbiology and Biomanufacturing ›› 2026, Vol. 6 ›› Issue (3) : 68

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Systems Microbiology and Biomanufacturing ›› 2026, Vol. 6 ›› Issue (3) :68 DOI: 10.1007/s43393-026-00464-6
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Enhancing γ-aminobutyric acid production by Enterococcus faecalis through atmospheric and room temperature plasma mutagenesis, adaptive evolution, and systematic fermentation optimization
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Enterococcus faecalis / ARTP mutagenesis / Adaptive evolution / Fermentation medium optimization

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Rumeng Han, Kun Qi, Shengming Gu, Qing Ding, Yimei Wang, Min Zhang, Mengkai Hu, Zhenglian Xue, Xiangfei Li. Enhancing γ-aminobutyric acid production by Enterococcus faecalis through atmospheric and room temperature plasma mutagenesis, adaptive evolution, and systematic fermentation optimization. Systems Microbiology and Biomanufacturing, 2026, 6(3): 68 DOI:10.1007/s43393-026-00464-6

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Funding

Natural Science Foundation of Anhui Province (No. 2508085QC105)

National College Student Innovation and Entrepreneurship Training Program (No. 201810363051)

Youth Fund of the National Natural Science Foundation of China (No. 32300059)

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Jiangnan University

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