Protein & Cell >

2024 , Vol. 15 >Issue 2: 149 - 155

DOI: https://doi.org/10.1093/procel/pwad041

Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain

  • Juan Zhang 1,2 ,
  • Dingfeng Li 3 ,
  • Keqiang He 4 ,
  • Qiang Liu , 3,5,6 ,
  • Zhongwen Xie , 2
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  • 1. School of Life Sciences, Anhui Agricultural University, Hefei 230036, China
  • 2. State Key Laboratory of Tea Plant Biology and Utilization, School of Tea and Food Sciences and Technology, Anhui Agricultural University, Hefei 230036, China
  • 3. Division of Life Sciences and Medicine, Hefei National Research Center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei 230026, China
  • 4. Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China
  • 5. Anhui Province Key Laboratory of Biomedical Aging Research, University of Science and Technology of China, Hefei 230026, China
  • 6. Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China
liuq2012@ustc.edu.cn
zhongwenxie@ahau.edu.cn

Accepted date: 25 Jun 2023

Published date: 15 Feb 2024

Copyright

2023 The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.
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Cite this article

Juan Zhang , Dingfeng Li , Keqiang He , Qiang Liu , Zhongwen Xie . Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain[J]. Protein & Cell, 2024 , 15(2) : 149 -155 . DOI: 10.1093/procel/pwad041

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