How erastin assassinates cells by ferroptosis revealed
Accepted date: 26 Apr 2022
Copyright
Boyi Gan . How erastin assassinates cells by ferroptosis revealed[J]. Protein & Cell, 2023 , 14(2) : 84 -86 . DOI: 10.1093/procel/pwac007
1 |
Dixon SJ, Lemberg KM, Lamprecht MR et al. Ferroptosis: an irondependent form of nonapoptotic cell death. Cell 2012;149:1060–1072.
|
2 |
Dolma S, Lessnick SL, Hahn WC et al. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell 2003;3:285–296.
|
3 |
Feng H, Stockwell BR. Unsolved mysteries: how does lipid peroxidation cause ferroptosis? PLoS Biol. 2018;16:e2006203.
|
4 |
Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol. 2021;22: 266–282.
|
5 |
Koppula P, Zhang Y, Zhuang L et al. Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer. Cancer Commun (Lond) 2018;38:12.
|
6 |
Koppula P, Zhuang L, Gan B. Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy. Protein Cell. 2021;12:599–620.
|
7 |
Lei G, Zhuang L, Gan B. Targeting ferroptosis as a vulnerability in cancer. Nat Rev Cancer. 2022;22:381–396.
|
8 |
Tang D, Chen X, Kang R et al. Ferroptosis: molecular mechanisms and health implications. Cell Res. 2021;31:107–125.
|
9 |
Yan R, Xie E, Li Y et al. The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Res. 2022;32:687–690.
|
10 |
Yang WS, SriRamaratnam R, Welsch ME et al. Regulation of ferroptotic cancer cell death by GPX4. Cell 2014;156:317–331.
|
/
〈 | 〉 |