Protein & Cell >

2022 , Vol. 13 >Issue 7: 540 - 547

DOI: https://doi.org/10.1007/s13238-021-00904-0

LETTER

Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis

  • Xiaolong Ma 1 ,
  • Jiacheng Deng 2 ,
  • Lulu Han 1 ,
  • Yuwei Song 1 ,
  • Yutong Miao 3 ,
  • Xing Du 1 ,
  • Guohui Dang 1 ,
  • Dongmin Yang 1 ,
  • Bitao Zhong 1 ,
  • Changtao Jiang 1 ,
  • Wei Kong 1 ,
  • Qingbo Xu 4 ,
  • Juan Feng , 1 ,
  • Xian Wang , 1
Expand
  • 1. Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University, Beijing 100191, China
  • 2. Cardiovascular Division, BHF Center of Vascular Regeneration, King’s College London, London, UK
  • 3. Department of Clinical Laboratory, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
  • 4. Department of Cardiology, The First Affiliated Hospital, Zhejiang University, Hangzhou 310003, China

Published date: 15 Jul 2022

Copyright

2022 The Author(s) 2022
Fold

Cite this article

Xiaolong Ma , Jiacheng Deng , Lulu Han , Yuwei Song , Yutong Miao , Xing Du , Guohui Dang , Dongmin Yang , Bitao Zhong , Changtao Jiang , Wei Kong , Qingbo Xu , Juan Feng , Xian Wang . Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis[J]. Protein & Cell, 2022 , 13(7) : 540 -547 . DOI: 10.1007/s13238-021-00904-0

References

Publishing order | Descend order by publishing year | Descend order by cited within
1
AltarejosJY, Montminy M (2011) CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12:141–151

DOI

2
DaiJ, LiW, ChangL, Zhang Z, TangC, WangN, ZhuY, WangX (2006) Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis. Free Radic Biol Med 41:1566–1577

DOI

3
DengT, LyonCJ, MinzeLJ, Lin J, ZouJ, LiuJZ, RenY, YinZ, Hamilton DJ, ReardonPR et al (2013) Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation. Cell Metab 17:411–422

DOI

4
DengJ, LuS, LiuH, LiuB, JiangC, Xu Q, FengJ, WangX (2017) Homocysteine activates B cells via regulating PKM2-dependent metabolic reprogramming. J Immunol 198:170–183

DOI

5
HuoY, LiJ, QinX, HuangY, WangX, Gottesman RF, TangG, WangB, ChenD, HeM et al (2015) Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial. JAMA 313:1325–1335

DOI

6
JinS, Guerrero-Juarez CF, ZhangL, ChangI, RamosR, KuanCH, Myung P, PlikusMV, NieQ (2021) Inference and analysis of cellcell communication using Cell Chat. Nat Commun 12:1088

DOI

7
KobayashiKS, van den Elsen PJ (2012) NLRC5: a key regulator of MHC class I-dependent immune responses. Nat Rev Immunol 12:813–820

DOI

8
LuoY, FengJ, XuQ, WangW, WangX (2016) NSun2 Deficiency protects endothelium from inflammation via mRNA methylation of ICAM-1. Circ Res 118:944–956

DOI

9
OkiS, OhtaT, ShioiG, Hatanaka H, OgasawaraO, OkudaY, Kawaji H, NakakiR, SeseJ, MenoC (2018) ChIP-Atlas: a data-mining suite powered by full integration of public ChIP-seq data. EMBO Rep 19

DOI

10
StuartT, Butler A, HoffmanP, HafemeisterC, Papalexi E, MauckWM, 3rd, HaoY, Stoeckius M, SmibertP, SatijaR (2019) Comprehensive Integration of Single-Cell Data. Cell 177:1888–1902 e1821

DOI

11
TruelsenT, Krarup LH, IversenHK, MensahGA, Feigin VL, SposatoLA, NaghaviM (2015) Causes of death data in the global burden of disease estimates for ischemic and hemorrhagic stroke. Neuroepidemiology 45:152–160

DOI

12
van der StoepN, Quinten E, van den ElsenPJ (2002) Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5’-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes. J Immunol 169:5061–5071

DOI

13
WeberG, Camagni G (1950) Frequency and entity of aortic atherosclerosis in chronic and acute endocarditis; inflammatory genesis of the atherosclerotic process. Arch De Vecchi Anat Patol 14:45–69

14
WinkelsH, Ehinger E, VassalloM, BuscherK, DinhHQ, KobiyamaK, Hamers AAJ, CochainC, VafadarnejadE, Saliba AE et al (2018) Atlas of the immune cell repertoire in mouse atherosclerosis defined by single-cell RNA-sequencing and mass cytometry. Circ Res 122:1675–1688

DOI

15
WooCW, SiowYL, OK, (2006) Homocysteine activates cAMPresponse element binding protein in HepG2 through cAMP/PKA signaling pathway. Arterioscler Thromb Vasc Biol 26:1043–1050

DOI

Options
Outlines

/

〈 〉