Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis

References

[1] AltarejosJY, Montminy M (2011) CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12:141–151

[2] DaiJ, LiW, ChangL, Zhang Z, TangC, WangN, ZhuY, WangX (2006) Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis. Free Radic Biol Med 41:1566–1577

[3] DengT, LyonCJ, MinzeLJ, Lin J, ZouJ, LiuJZ, RenY, YinZ, Hamilton DJ, ReardonPR et al (2013) Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation. Cell Metab 17:411–422

[4] DengJ, LuS, LiuH, LiuB, JiangC, Xu Q, FengJ, WangX (2017) Homocysteine activates B cells via regulating PKM2-dependent metabolic reprogramming. J Immunol 198:170–183

[5] HuoY, LiJ, QinX, HuangY, WangX, Gottesman RF, TangG, WangB, ChenD, HeM et al (2015) Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial. JAMA 313:1325–1335

[6] JinS, Guerrero-Juarez CF, ZhangL, ChangI, RamosR, KuanCH, Myung P, PlikusMV, NieQ (2021) Inference and analysis of cellcell communication using Cell Chat. Nat Commun 12:1088

[7] KobayashiKS, van den Elsen PJ (2012) NLRC5: a key regulator of MHC class I-dependent immune responses. Nat Rev Immunol 12:813–820

[8] LuoY, FengJ, XuQ, WangW, WangX (2016) NSun2 Deficiency protects endothelium from inflammation via mRNA methylation of ICAM-1. Circ Res 118:944–956

[9] OkiS, OhtaT, ShioiG, Hatanaka H, OgasawaraO, OkudaY, Kawaji H, NakakiR, SeseJ, MenoC (2018) ChIP-Atlas: a data-mining suite powered by full integration of public ChIP-seq data. EMBO Rep 19

[10] StuartT, Butler A, HoffmanP, HafemeisterC, Papalexi E, MauckWM, 3rd, HaoY, Stoeckius M, SmibertP, SatijaR (2019) Comprehensive Integration of Single-Cell Data. Cell 177:1888–1902 e1821

[11] TruelsenT, Krarup LH, IversenHK, MensahGA, Feigin VL, SposatoLA, NaghaviM (2015) Causes of death data in the global burden of disease estimates for ischemic and hemorrhagic stroke. Neuroepidemiology 45:152–160

[12] van der StoepN, Quinten E, van den ElsenPJ (2002) Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5’-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes. J Immunol 169:5061–5071

[13] WeberG, Camagni G (1950) Frequency and entity of aortic atherosclerosis in chronic and acute endocarditis; inflammatory genesis of the atherosclerotic process. Arch De Vecchi Anat Patol 14:45–69

[14] WinkelsH, Ehinger E, VassalloM, BuscherK, DinhHQ, KobiyamaK, Hamers AAJ, CochainC, VafadarnejadE, Saliba AE et al (2018) Atlas of the immune cell repertoire in mouse atherosclerosis defined by single-cell RNA-sequencing and mass cytometry. Circ Res 122:1675–1688

[15] WooCW, SiowYL, OK, (2006) Homocysteine activates cAMPresponse element binding protein in HepG2 through cAMP/PKA signaling pathway. Arterioscler Thromb Vasc Biol 26:1043–1050

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