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Comprehensive analysis of RNA-seq and whole genome sequencing data reveals no evidence for SARS-CoV-2 integrating into host genome

  • Yu-Sheng Chen 1,2,4 ,
  • Shuaiyao Lu 3 ,
  • Bing Zhang 1,2 ,
  • Tingfu Du 3 ,
  • Wen-Jie Li 1,2 ,
  • Meng Lei 1,2 ,
  • Yanan Zhou 3 ,
  • Yong Zhang 3 ,
  • Penghui Liu 3 ,
  • Yong-Qiao Sun 1,2 ,
  • Yong-Liang Zhao 1,2,5 ,
  • Ying Yang , 1,2,4,5 ,
  • Xiaozhong Peng , 3,6 ,
  • Yun-Gui Yang , 1,2,4,5
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  • 1. CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
  • 2. China National Center for Bioinformation, Beijing 100101, China
  • 3. National Kunming High-level Biosafety Primate Research Center, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650031, China
  • 4. Institute of Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China
  • 5. University of Chinese Academy of Sciences, Beijing 100049, China
  • 6. State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking, Union Medical College, Beijing 100005, China

Published date: 15 May 2022

Copyright

2021 The Author(s)

Cite this article

Yu-Sheng Chen , Shuaiyao Lu , Bing Zhang , Tingfu Du , Wen-Jie Li , Meng Lei , Yanan Zhou , Yong Zhang , Penghui Liu , Yong-Qiao Sun , Yong-Liang Zhao , Ying Yang , Xiaozhong Peng , Yun-Gui Yang . Comprehensive analysis of RNA-seq and whole genome sequencing data reveals no evidence for SARS-CoV-2 integrating into host genome[J]. Protein & Cell, 2022 , 13(5) : 379 -385 . DOI: 10.1007/s13238-021-00861-8

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