Protein & Cell >

2022 , Vol. 13 >Issue 2: 148 - 154

DOI: https://doi.org/10.1007/s13238-021-00844-9

LETTER

Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes

  • Beili Chen 1,5 ,
  • Jianying Guo 2,6 ,
  • Ting Wang 2,6 ,
  • Qianhui Lee 3 ,
  • Jia Ming 2 ,
  • Fangfang Ding 1,5 ,
  • Haitao Li 2,6 ,
  • Zhiguo Zhang , 1,5 ,
  • Lin Li , 4 ,
  • Yunxia Cao , 1,5 ,
  • Jie Na , 2
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  • 1. Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
  • 2. School of Medicine, Tsinghua University, Beijing 100084, China
  • 3. Department of Chemistry, Tsinghua University, Beijing 100084, China
  • 4. Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • 5. NHC Key Laboratory of study on abnormal gametes and reproductive tract, Anhui Medical University, Hefei 230032, China
  • 6. Tsinghua-Peking Center for Life Sciences, Beijing 100084, China

Accepted date: 23 Mar 2021

Published date: 15 Feb 2022

Copyright

2021 The Author(s)
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Cite this article

Beili Chen , Jianying Guo , Ting Wang , Qianhui Lee , Jia Ming , Fangfang Ding , Haitao Li , Zhiguo Zhang , Lin Li , Yunxia Cao , Jie Na . Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes[J]. Protein & Cell, 2022 , 13(2) : 148 -154 . DOI: 10.1007/s13238-021-00844-9

References

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