LETTER

Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development

  • Lin Zhao 1 ,
  • Songguo Xue 2 ,
  • Zhongyuan Yao 3 ,
  • Juanzi Shi 4 ,
  • Biaobang Chen 5 ,
  • Ling Wu 6 ,
  • Lihua Sun 2 ,
  • Yao Xu 2 ,
  • Zheng Yan 6 ,
  • Bin Li 6 ,
  • Xiaoyan Mao 6 ,
  • Jing Fu 7 ,
  • Zhihua Zhang 1 ,
  • Jian Mu 1 ,
  • Wenjing Wang 1 ,
  • Jing Du 5 ,
  • Shuai Liu 8 ,
  • Jie Dong 1 ,
  • Weijie Wang 1 ,
  • Qiaoli Li 1 ,
  • Lin He 9 ,
  • Li Jin 10 ,
  • Xiaozhen Liang 8 ,
  • Yanping Kuang 6 ,
  • Xiaoxi Sun 7 ,
  • Lei Wang , 1,11,12 ,
  • Qing Sang , 1,11
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  • 1. Institute of Pediatrics, Children’s Hospital of Fudan University and the Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and metabolism, Ministry of Science and technology and Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China
  • 2. Center of Assisted Reproduction, Shanghai East hospital, Tongji University, Shanghai 200120, China
  • 3. The Reproductive Medical Center of Xiangya Hospital, Central South University, Changsha 41008, China
  • 4. Reproductive Medicine Center, Shaanxi Maternal and Child Care Service Center, Xi’an 710069, China
  • 5. NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, Shanghai 200032, China
  • 6. Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China
  • 7. Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China
  • 8. Key Laboratory of Molecular Virology Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
  • 9. Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China
  • 10. State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China
  • 11. Zhuhai Fudan Innovation Institute, Zhuhai 519000, China
  • 12. Shanghai Center for Women and Children’s Health, Shanghai 200062, China

Published date: 15 Dec 2020

Copyright

2020 The Author(s)

Cite this article

Lin Zhao , Songguo Xue , Zhongyuan Yao , Juanzi Shi , Biaobang Chen , Ling Wu , Lihua Sun , Yao Xu , Zheng Yan , Bin Li , Xiaoyan Mao , Jing Fu , Zhihua Zhang , Jian Mu , Wenjing Wang , Jing Du , Shuai Liu , Jie Dong , Weijie Wang , Qiaoli Li , Lin He , Li Jin , Xiaozhen Liang , Yanping Kuang , Xiaoxi Sun , Lei Wang , Qing Sang . Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development[J]. Protein & Cell, 2020 , 11(12) : 921 -927 . DOI: 10.1007/s13238-020-00756-0

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