Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development

Lin Zhao; Songguo Xue; Zhongyuan Yao; Juanzi Shi; Biaobang Chen; Ling Wu; Lihua Sun; Yao Xu; Zheng Yan; Bin Li; Xiaoyan Mao; Jing Fu; Zhihua Zhang; Jian Mu; Wenjing Wang; Jing Du; Shuai Liu; Jie Dong; Weijie Wang; Qiaoli Li; Lin He; Li Jin; Xiaozhen Liang; Yanping Kuang; Xiaoxi Sun; Lei Wang; Qing Sang

doi:10.1007/s13238-020-00756-0

Protein Cell ›› 2020, Vol. 11 ›› Issue (12) : 921 -927. DOI: 10.1007/s13238-020-00756-0

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Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development

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¹. Institute of Pediatrics, Children’s Hospital of Fudan University and the Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and metabolism, Ministry of Science and technology and Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China

². Center of Assisted Reproduction, Shanghai East hospital, Tongji University, Shanghai 200120, China

³. The Reproductive Medical Center of Xiangya Hospital, Central South University, Changsha 41008, China

⁴. Reproductive Medicine Center, Shaanxi Maternal and Child Care Service Center, Xi’an 710069, China

⁵. NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, Shanghai 200032, China

⁶. Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China

⁷. Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China

⁸. Key Laboratory of Molecular Virology Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China

⁹. Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China

¹⁰. State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China

¹¹. Zhuhai Fudan Innovation Institute, Zhuhai 519000, China

¹². Shanghai Center for Women and Children’s Health, Shanghai 200062, China

wangleiwanglei@fudan.edu.cn

sangqing@fudan.edu.cn

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Lin Zhao, Songguo Xue, Zhongyuan Yao, Juanzi Shi, Biaobang Chen, Ling Wu, Lihua Sun, Yao Xu, Zheng Yan, Bin Li, Xiaoyan Mao, Jing Fu, Zhihua Zhang, Jian Mu, Wenjing Wang, Jing Du, Shuai Liu, Jie Dong, Weijie Wang, Qiaoli Li, Lin He, Li Jin, Xiaozhen Liang, Yanping Kuang, Xiaoxi Sun, Lei Wang, Qing Sang. Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development. Protein Cell, 2020, 11(12): 921-927 DOI:10.1007/s13238-020-00756-0

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