Protein & Cell >

2020 , Vol. 11 >Issue 7: 534 - 539

DOI: https://doi.org/10.1007/s13238-020-00732-8

LETTER

FAK-targeting PROTAC as a chemical tool for the investigation of non-enzymatic FAK function in mice

  • Hongying Gao 1,2 ,
  • Chunwei Zheng 3 ,
  • Jian Du 4 ,
  • Yue Wu 1 ,
  • Yonghui Sun 1 ,
  • Chunsheng Han , 3,5 ,
  • Kehkooi Kee , 4 ,
  • Yu Rao , 1
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  • 1. MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry Chemical Biology, Tsinghua University, Beijing 100084, China
  • 2. Tsinghua University-Peking University Joint Center for Life Sciences, Beijing 100084, China
  • 3. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100084, China
  • 4. Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China
  • 5. University of Chinese Academy of Sciences, Savaid Medical School, Beijing 100049, China

Published date: 15 Jul 2020

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2020 The Author(s)
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Cite this article

Hongying Gao , Chunwei Zheng , Jian Du , Yue Wu , Yonghui Sun , Chunsheng Han , Kehkooi Kee , Yu Rao . FAK-targeting PROTAC as a chemical tool for the investigation of non-enzymatic FAK function in mice[J]. Protein & Cell, 2020 , 11(7) : 534 -539 . DOI: 10.1007/s13238-020-00732-8

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