Protein & Cell >

2018 , Vol. 9 >Issue 11: 971 - 975

DOI: https://doi.org/10.1007/s13238-017-0502-7

LETTER

Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target

  • Qingqing Zhang 1,7 ,
  • Huijuan Liu 1 ,
  • Xiang Liu 2 ,
  • Dunquan Jiang 1 ,
  • Bingjie Zhang 3 ,
  • Hongliang Tian 4 ,
  • Cheng Yang 2 ,
  • Luke W. Guddat 5 ,
  • Haitao Yang 4 ,
  • Kaixia Mi 3 ,
  • Zihe Rao , 1,2,6
Expand
  • 1. College of Life Sciences, Nankai University, Tianjin 300071, China
  • 2. College of Pharmacy, Nankai University, Tianjin 300071, China
  • 3. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
  • 4. School of Life Sciences, Tianjin University, Tianjin 300072, China
  • 5. School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia
  • 6. Laboratory of Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China
  • 7. Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin 300457, China

Published date: 29 Nov 2018

Copyright

2018 The Author(s) 2018. This article is an open access publication
Fold

Cite this article

Qingqing Zhang , Huijuan Liu , Xiang Liu , Dunquan Jiang , Bingjie Zhang , Hongliang Tian , Cheng Yang , Luke W. Guddat , Haitao Yang , Kaixia Mi , Zihe Rao . Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target[J]. Protein & Cell, 2018 , 9(11) : 971 -975 . DOI: 10.1007/s13238-017-0502-7

References

Publishing order | Descend order by publishing year | Descend order by cited within
1
Alekshun, M.N., and Levy, S.B. (2007). Molecular mechanisms of antibacterial multidrug resistance. Cell 128, 1037–1050.

DOI

2
Alimuddin Zumla, Andrew George, Virendra Sharma, Nick Herbert, and Masham, B. (2013). WHO’s 2013 global report on tuberculosis: successes, threats, and opportunities. Lancet 382, 1765–1767.

DOI

3
Black, P.A., Warren, R.M., Louw, G.E., van Helden, P.D., Victor, T.C., and Kana, B.D. (2014). Energy metabolism and drug efflux in Mycobacterium tuberculosis. Antimicrob Agents Chemother 58, 2491–2503.

DOI

4
Blair, J.M., Webber, M.A., Baylay, A.J., Ogbolu, D.O., and Piddock, L.J. (2015). Molecular mechanisms of antibiotic resistance. Nat Rev Microbiol 13, 42–51.

DOI

5
Buriankova, K., Doucet-Populaire, F., Dorson, O., Gondran, A., Ghnassia, J.C., Weiser, J., and Pernodet, J.L. (2003). Molecular Basis of Intrinsic Macrolide Resistance in the Mycobacterium tuberculosis Complex. Antimicrob Agents Chemother 48, 143–150.

DOI

6
Chen, S., Huai, P., Wang, X., Zhong, J., Wang, X., Wang, K., Wang, L., Jiang, S., Li, J., Peng, Y., (2013). Risk factors for multidrug resistance among previously treated patients with tuberculosis in eastern China: a case-control study. Int J Infect Dis 17, e1116–e1120.

DOI

7
Dassa, E., and Bouige, P. (2001). The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms. Res Microbiol 152, 211–229.

DOI

8
Dong, Y., Qiu, X., Shaw, N., Xu, Y., Sun, Y., Li, X., Li, J., and Rao, Z. (2015). Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosisby flavonoid inhibitors. Protein Cell 6, 504–517.

DOI

9
Günther, G. (2014). Multidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges. Clin Med 14, 279–285.

DOI

10
Kerr, I. D., Reynolds, E.D., and Cove, J.H. (2005). ABC proteins and antibiotic drug resistance: is it all about transport? Biochem Soc 33, 1000–1002.

DOI

11
Lin, D.Y., Huang, S., and Chen, J. (2015). Crystal structures of a polypeptide processing and secretion transporter. Nature 523, 425–430.

DOI

12
Nunez-Samudio, V., and Chesneau, O. (2013). Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. Res Microbiol 164, 226–235.

DOI

13
Shim, T.S., and Jo, K.-W. (2013). Medical treatment of pulmonary multidrug-resistant tuberculosis. Infect Chemother 45, 367–374.

DOI

14
Sharkey, L.K., Edwards, T.A., and O’Neill, A.J. (2016). ABC-F proteins mediate antibiotic resistance through ribosomal protection. MBio 7, e01975.

DOI

15
WHO (2014). Global tuberculosis report 2014 (Geneva, World Health Organization).

Options
Outlines

/

〈 〉