LETTER

Effective and precise adenine base editing in mouse zygotes

  • Puping Liang , 1,2 ,
  • Hongwei Sun 1 ,
  • Xiya Zhang 1 ,
  • Xiaowei Xie 1 ,
  • Jinran Zhang 1 ,
  • Yaofu Bai 1 ,
  • Xueling Ouyang 1 ,
  • Shengyao Zhi 1 ,
  • Yuanyan Xiong 1 ,
  • Wenbin Ma 1 ,
  • Dan Liu 4 ,
  • Junjiu Huang , 1,2,3 ,
  • Zhou Songyang , 1,2,3,4
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  • 1. Key Laboratory of Gene Engineering of the Ministry of Education, Guangzhou Key Laboratory of Healthy Aging Research and SYSU-BCM Joint Research Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China
  • 2. Key Laboratory of Reproductive Medicine of Guangdong Province, School of Life Sciences and the First Affiliated Hospital, Sun Yatsen University, Guangzhou 510275, China
  • 3. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
  • 4. Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA

Published date: 21 Sep 2018

Copyright

2018 The Author(s)

Cite this article

Puping Liang , Hongwei Sun , Xiya Zhang , Xiaowei Xie , Jinran Zhang , Yaofu Bai , Xueling Ouyang , Shengyao Zhi , Yuanyan Xiong , Wenbin Ma , Dan Liu , Junjiu Huang , Zhou Songyang . Effective and precise adenine base editing in mouse zygotes[J]. Protein & Cell, 2018 , 9(9) : 808 -813 . DOI: 10.1007/s13238-018-0566-z

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