[1] Aasen, T., Raya, A., Barrero, M.J., Garreta, E., Consiglio, A., Gonzalez, F., Vassena, R., Bili?, J., Pekarik, V., Tiscornia, G., (2008). Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 26, 1276-1284 .18931654
[2] Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., Chiba, T., and Yamanaka, S. (2008). Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321, 699-702 .18276851
[3] Baumann, K. (2010). Stem cells: holding on to the memories. Nat Rev Mol Cell Biol 11, 601.20717148
[4] Blackburn, D., Sargsyan, S., Monk, P.N., and Shaw, P.J. (2009). Astrocyte function and role in motor neuron disease: a future therapeutic target? Glia 57, 1251-1264 .19373940
[5] Caldwell, M.A., He, X., Wilkie, N., Pollack, S., Marshall, G., Wafford, K.A., and Svendsen, C.N. (2001). Growth factors regulate the survival and fate of cells derived from human neurospheres. Nat Biotechnol 19, 475-479 .11329020
[6] Carey, B.W., Markoulaki, S., Hanna, J., Saha, K., Gao, Q., Mitalipova, M., and Jaenisch, R. (2009). Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc Natl Acad Sci U S A 106, 157-162 .19109433
[7] Carleton, A., Petreanu, L.T., Lansford, R., Alvarez-Buylla, A., and Lledo, P.M. (2003). Becoming a new neuron in the adult olfactory bulb. Nat Neurosci 6, 507-518 .12704391
[8] Fawcett, J.W. (1997). Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system. Cell Tissue Res 290, 371-377 .9321700
[9] Ghorpade, A., Holter, S., Borgmann, K., Persidsky, R., and Wu, L. (2003). HIV-1 and IL-1 beta regulate Fas ligand expression in human astrocytes through the NF-kappa B pathway. J Neuroimmunol 141, 141-149 .12965265
[10] Ghosh, Z., Wilson, K.D., Wu, Y., Hu, S., Quertermous, T., and Wu, J.C. (2010). Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells. PLoS One 5, e8975.20126639
[11] Hanna, J., Markoulaki, S., Schorderet, P., Carey, B.W., Beard, C., Wernig, M., Creyghton, M.P., Steine, E.J., Cassady, J.P., Foreman, R., (2008). Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133, 250-264 .18423197
[12] Hirsch, E.C., Breidert, T., Rousselet, E., Hunot, S., Hartmann, A., and Michel, P.P. (2003). The role of glial reaction and inflammation in Parkinson’s disease. Ann N Y Acad Sci 991, 214-228 .12846989
[13] Hu, Q., Friedrich, A.M., Johnson, L.V., and Clegg, D.O. (2010). Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells 28, 1981-1991 .20882530
[14] Jain, M., Armstrong, R.J., Tyers, P., Barker, R.A., and Rosser, A.E. (2003). GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro. Exp Neurol 182, 113-123 .12821381
[15] Johe, K.K., Hazel, T.G., Muller, T., Dugich-Djordjevic, M.M., and McKay, R.D. (1996). Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev 10, 3129-3140 .8985182
[16] Kim, J.B., Greber, B., Araúzo-Bravo, M.J., Meyer, J., Park, K.I., Zaehres, H., and Sch?ler, H.R. (2009a). Direct reprogramming of human neural stem cells by OCT4. Nature 461, 649-3 .19718018
[17] Kim, J.B., Sebastiano, V., Wu, G., Araúzo-Bravo, M.J., Sasse, P., Gentile, L., Ko, K., Ruau, D., Ehrich, M., van den Boom, D., (2009b). Oct4-induced pluripotency in adult neural stem cells. Cell 136, 411-419 .19203577
[18] Kim, J.B., Zaehres, H., Araúzo-Bravo, M.J., and Sch?ler, H.R. (2009c). Generation of induced pluripotent stem cells from neural stem cells. Nat Protoc 4, 1464-1470 .19798081
[19] Kim, J.B., Zaehres, H., Wu, G., Gentile, L., Ko, K., Sebastiano, V., Araúzo-Bravo, M.J., Ruau, D., Han, D.W., Zenke, M., (2008). Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454, 646-650 .18594515
[20] Kim, K., Doi, A., Wen, B., Ng, K., Zhao, R., Cahan, P., Kim, J., Aryee, M.J., Ji, H., Ehrlich, L.I., (2010). Epigenetic memory in induced pluripotent stem cells. Nature 467, 285-290 .20644535
[21] Lee, S.H., Lumelsky, N., Studer, L., Auerbach, J.M., and McKay, R.D. (2000). Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 18, 675-679 .10835609
[22] Lois, C., and Alvarez-Buylla, A. (1994). Long-distance neuronal migration in the adult mammalian brain. Science 264, 1145-1148 .8178174
[23] Moon, J.H., Yoon, B.S., Kim, B., Park, G., Jung, H.Y., Maeng, I., Jun, E.K., Yoo, S.J., Kim, A., Oh, S., (2008). Induction of neural stem cell-like cells (NSCLCs) from mouse astrocytes by Bmi1. Biochem Biophys Res Commun 371, 267-272 .18439910
[24] Pereira, C.F., Terranova, R., Ryan, N.K., Santos, J., Morris, K.J., Cui, W., Merkenschlager, M., and Fisher, A.G. (2008). Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2. PLoS Genet 4, e1000170.18773085
[25] Polo, J.M., Liu, S., Figueroa, M.E., Kulalert, W., Eminli, S., Tan, K.Y., Apostolou, E., Stadtfeld, M., Li, Y., Shioda, T., (2010). Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol 28, 848-855 .20644536
[26] Ridet, J.L., Malhotra, S.K., Privat, A., and Gage, F.H. (1997). Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20, 570-577 .9416670
[27] Rodríguez, J.J., Olabarria, M., Chvatal, A., and Verkhratsky, A. (2009). Astroglia in dementia and Alzheimer’s disease. Cell Death Differ 16, 378-385 .19057621
[28] Sher, F., Boddeke, E., and Copray, S. (2010). Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells. Cell Reprogram . Oct27. [Epub ahead of print]20979531
[29] Stadtfeld, M., Brennand, K., and Hochedlinger, K. (2008). Reprogramming of pancreatic beta cells into induced pluripotent stem cells. Curr Biol 18, 890-894 .18501604
[30] Studer, L., Tabar, V., and McKay, R.D. (1998). Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci 1, 290-295 .10195162
[31] Takahashi, K., Okita, K., Nakagawa, M., and Yamanaka, S. (2007). Induction of pluripotent stem cells from fibroblast cultures. Nat Protoc 2, 3081-3089 .18079707
[32] Takahashi, K., and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 .16904174
[33] Tian, C., Gao, P., Zheng, Y., Yue, W., Wang, X., Jin, H., and Chen, Q. (2008). Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death. Cell Res 18, 458-471 .18157160
[34] Utikal, J., Maherali, N., Kulalert, W., and Hochedlinger, K. (2009). Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. J Cell Sci 122, 3502-3510 .19723802
[35] Vicario-Abejón, C., Johe, K.K., Hazel, T.G., Collazo, D., and McKay, R.D. (1995). Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron 15, 105-114 .7619514
[36] Vitvitsky, V., Thomas, M., Ghorpade, A., Gendelman, H.E., and Banerjee, R. (2006). A functional transsulfuration pathway in the brain links to glutathione homeostasis. J Biol Chem 281, 35785-35793 .17005561
[37] Wakayama, T., Tabar, V., Rodriguez, I., Perry, A.C., Studer, L., and Mombaerts, P. (2001). Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science 292, 740-743 .11326103
[38] Ye, Z., Zhan, H., Mali, P., Dowey, S., Williams, D.M., Jang, Y.Y., Dang, C.V., Spivak, J.L., Moliterno, A.R., and Cheng, L. (2009). Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 .19797525
[39] Yu, J., Vodyanik, M.A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J.L., Tian, S., Nie, J., Jonsdottir, G.A., Ruotti, V., Stewart, R., (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920 .18029452