LETTER

The PilZ domain of MrkH represents a novel DNA binding motif

Expand

Published date: 24 Oct 2016

Copyright

2016 The Author(s) 2016. This article is published with open access at Springerlink.com and journal.hep.com.cn

Cite this article

. The PilZ domain of MrkH represents a novel DNA binding motif[J]. Protein & Cell, 2016 , 7(10) : 766 -772 . DOI: 10.1007/s13238-016-0317-y

1
Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A (2007) The structural basis of cyclic diguanylate signal transduction by PilZ domains. Embo J 26:5153–5166

DOI

2
Christen M, Christen B, Allan MG, Folcher M, Jeno P, Grzesiek S, Jenal U (2007) DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in caulobacter crescentus. Proc Natl Acad Sci USA 104:7729

DOI

3
Holm L, Rosenstrom P (2010) Dali server: conservation mapping in 3D. Nucleic Acids Res 38:W545–W549

4
Johnson JG, Murphy CN, Sippy J, Johnson TJ, Clegg S (2011) Type 3 fimbriae and biofilm formation are regulated by the transcriptional regulators MrkHI in Klebsiella pneumoniae. J Bacteriol 193:3453–3460

DOI

5
Ko J, Ryu KS, Kim H, Shin JS, Lee JO, Cheong C, Choi BS (2010) Structure of PP4397 reveals the molecular basis for different c-di-GMP binding modes by Pilz domain proteins. J Mol Biol 398:97–110

DOI

6
Murphy CN, Clegg S (2012) Klebsiella pneumoniae and type 3 fimbriae: nosocomial infection, regulation and biofilm formation. Futur Microbiol 7:1234

7
Ryan RP, Tolker-Nielsen T, Dow JM (2012) When the PilZ don't work: effectors for cyclic di-GMP action in bacteria. Trends Microbiol 20:235–242

DOI

8
Stivala A, Wybrow M, Wirth A, Whisstock JC, Stuckey PJ (2011) Automatic generation of protein structure cartoons with Proorigami. Bioinformatics 27:3315–3316

DOI

9
Tan JWH, Wilksch JJ, Hocking DM, Wang N, Srikhanta YN, Tauschek M, Lithgow T, Robins-Browne RM, Yang J, Strugnell RA (2015) Positive autoregulation of mrkHI by the cyclic Di-GMPdependent MrkH protein in the biofilm regulatory circuit of Klebsiella pneumoniae. J Bacteriol 197:1659–1667

DOI

10
Tuszynska I, Magnus M, Jonak K, Dawson W, Bujnicki JM (2015) NPDock: a web server for protein–nucleic acid docking. Nucleic Acids Res 43(W1):W425–W430

11
Whitney JC, Whitfield GB, Marmont LS, Yip P, Neculai AM, Lobsanov YD, Robinson H, Ohman DE, Howell PL (2015) Dimeric c-di-GMP is required for post-translational regulation of alginate production in pseudomonas aeruginosa. J Biol Chem 290:12451–12462

DOI

12
Wilksch JJ, Yang J, Clements A, Gabbe JL, Short KR, Cao H, Cavaliere R, James CE, Whitchurch CB, Schembri MA (2011) MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression. PLoS Pathog 7:e1002204

13
Yang J, Wilksch JJ, Tan JW, Hocking DM, Webb CT, Lithgow T, Robins-Browne RM, Strugnell RA (2013) Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein. PLoS One 8:e79038

Outlines

/