LETTER

Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride

  • Linlin Zhao 1 ,
  • Shuqing Wang 2 ,
  • Lingyu Du 1 ,
  • Jyoti Dev 3 ,
  • Liujuan Zhou 1 ,
  • Zhijun Liu 1 ,
  • James J. Chou , 1,3 ,
  • Bo OuYang , 1,4
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  • 1. National Center for Protein Science, State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China
  • 2. Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China
  • 3. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
  • 4. Shanghai Science Research Center, Chinese Academy of Sciences, Shanghai 201204, China

Published date: 09 May 2016

Copyright

2014 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cite this article

Linlin Zhao , Shuqing Wang , Lingyu Du , Jyoti Dev , Liujuan Zhou , Zhijun Liu , James J. Chou , Bo OuYang . Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride[J]. Protein & Cell, 2016 , 7(4) : 300 -304 . DOI: 10.1007/s13238-016-0256-7

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