LETTER

Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach

  • Yuwei Bai 1,2 ,
  • Shinya Tashiro 3 ,
  • Satoru Nagatoishi 3 ,
  • Toru Suzuki 1,2 ,
  • Dongke Yan 1,2 ,
  • Ruihua Liu 1,2 ,
  • Kouhei Tsumoto , 3 ,
  • Mark Bartlam , 1,2
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  • 1. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China
  • 2. College of Life Sciences, Nankai University, Tianjin 300071, China
  • 3. Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108–8639, Japan
  • 4. Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Onna-son, Kunigami, Okinawa 904-0412, Japan

Published date: 04 Jan 2016

Copyright

2014 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cite this article

Yuwei Bai , Shinya Tashiro , Satoru Nagatoishi , Toru Suzuki , Dongke Yan , Ruihua Liu , Kouhei Tsumoto , Mark Bartlam . Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach[J]. Protein & Cell, 2015 , 06(12) : 924 -928 . DOI: 10.1007/s13238-015-0225-6

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