Step-wise organization of genomic nuclear speckle-associated domains during mammalian embryonic development

Mengyao Kang , Tongzhen Zhang , Chao Ning , Yibing Bao , Zhenbo Liu , Lei Gao , Linghui Luan , Chao Wang , Jiang Liu , Yuwen Ke

Protein Cell ›› 2025, Vol. 16 ›› Issue (9) : 815 -821.

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Protein Cell ›› 2025, Vol. 16 ›› Issue (9) : 815 -821. DOI: 10.1093/procel/pwaf015
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Step-wise organization of genomic nuclear speckle-associated domains during mammalian embryonic development

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Mengyao Kang, Tongzhen Zhang, Chao Ning, Yibing Bao, Zhenbo Liu, Lei Gao, Linghui Luan, Chao Wang, Jiang Liu, Yuwen Ke. Step-wise organization of genomic nuclear speckle-associated domains during mammalian embryonic development. Protein Cell, 2025, 16(9): 815-821 DOI:10.1093/procel/pwaf015

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References

[1]

Borsos M , Perricone SM , Schauer T et al. Genome-lamina interactions are established de novo in the early mouse embryo. Nature 2019; 569: 729- 733.

[2]

Chen Y , Belmont AS . Genome organization around nuclear speckles. Curr Opin Genet Dev 2019; 55: 91- 99.

[3]

Cuartero S , Stik G , Stadhouders R . Three-dimensional genome organization in immune cell fate and function. Nat Rev Immunol 2023; 23: 206- 221.

[4]

Fraschilla I , Jeffrey KL . The Speckled Protein (SP) family:immunity's chromatin readers. Trends Immunol 2020; 41: 572- 585.

[5]

Gao D , Zhu B , Cao X et al. Roles of NIPBL in maintenance of genome stability. Seminars in Cell & Developmental Biology 2018; 90: 181- 186.

[6]

Gordon JM , Phizicky DV , Neugebauer KM . Nuclear mechanisms of gene expression control:pre-mRNA splicing as a life or death decision. Curr Opin Genet Dev 2021; 67: 67- 76.

[7]

Inoue A , Jiang L , Lu F et al. Maternal H3K27me3 controls DNA methylation-independent imprinting. Nature 2017; 547: 419- 424.

[8]

Ke Y , Xu Y , Chen X et al. 3D chromatin structures of mature gametes and structural reprogramming during mammalian embryogenesis. Cell 2017; 170: 367- 381.e20.

[9]

Kravchenko P , Tachibana K . Rise and SINE:roles of transcription factors and retrotransposons in zygotic genome activation. Nat Rev Mol Cell Biol 2025; 26: 68- 79.

[10]

Lallena MJ , Correas I et al. Transcription-dependent redistribution of nuclear protein 4.1 to SC35-enriched nuclear domains. J Cell Sci 1997; 110: 239- 247.

[11]

Lee JT , Bartolomei MS . X-inactivation, imprinting, and long noncoding RNAs in health and disease. Cell 2013; 152: 1308- 1323.

[12]

Payne AC , Chiang ZD , Reginato PL et al. In situ genome sequencing resolves DNA sequence and structure in intact biological samples. Science 2021; 371: eaay3446.

[13]

Quinodoz SA , Ollikainen N , Tabak B et al. Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus. Cell 2018; 174: 744- 757.e724.

[14]

Schrode N , Saiz N , Di Talia S et al. GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. Dev Cell 2014; 29: 454- 467.

[15]

Wang Y , Elsherbiny A , Kessler L et al. Lamin A/C-dependent chromatin architecture safeguards naive pluripotency to prevent aberrant cardiovascular cell fate and function. Nat Commun 2022; 13: 6663.

[16]

Yu R , Roseman S , Siegenfeld AP et al. CTCF/cohesin organize the ground state of chromatin-nuclear speckle association. bioRxiv 2023.

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