An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes

Weijia Mao; Pei Wang; Lei Zhou; Dongxu Li; Xiangyang Li; Xin Lou; Xingxu Huang; Feng Wang; Yanli Zhang; Jianghuai Liu; Yongjie Wan

doi:10.1093/procel/pwaf006

Protein Cell ›› 2025, Vol. 16 ›› Issue (8) : 732 -738. DOI: 10.1093/procel/pwaf006

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An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes

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Weijia Mao, Pei Wang, Lei Zhou, Dongxu Li, Xiangyang Li, Xin Lou, Xingxu Huang, Feng Wang, Yanli Zhang, Jianghuai Liu, Yongjie Wan. An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes. Protein Cell, 2025, 16(8): 732-738 DOI:10.1093/procel/pwaf006

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References

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