Join the club: ORP8 is a lipophagy receptor

Zheng Wang , Hong Zhang

Protein Cell ›› 2023, Vol. 14 ›› Issue (9) : 632 -634.

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Protein Cell ›› 2023, Vol. 14 ›› Issue (9) : 632 -634. DOI: 10.1093/procel/pwad005
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Join the club: ORP8 is a lipophagy receptor

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Zheng Wang, Hong Zhang. Join the club: ORP8 is a lipophagy receptor. Protein Cell, 2023, 14(9): 632-634 DOI:10.1093/procel/pwad005

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References

[1]

Chino H, Mizushima N. ER-Phagy: quality and quantity control of the endoplasmic reticulum by autophagy. Cold Spring Harb Perspect Biol 2023;15:a041256.

[2]

Chung J, Torta F, Masai K et al. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts. Science 2015;349:428–432.

[3]

Guyard V, Monteiro-Cardoso VF, Omrane M et al. ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintainance at ER-mitochondria contact sites. J Cell Biol 2022;221:e202112107.

[4]

Johansen T, Lamark T. Selective autophagy: ATG8 family proteins, LIR motifs and cargo receptors. J Mol Biol 2020;432:80–103.

[5]

Nakatogawa H. Mechanisms governing autophagosome biogenesis. Nat Rev Mol Cell Biol 2020;21:439–458.

[6]

Pu M, Zheng W, Zhang H et al. ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover. Protein Cell 2022;14:653–667.

[7]

Sawa-Makarska J, Abert C, Romanov J et al. Cargo binding to Atg19 unmasks additional Atg8 binding sites to mediate membrane–cargo apposition during selective autophagy. Nat Cell Biol 2014;16:425–433.

[8]

Vargas JNS, Hamasaki M, Kawabata T et al. The mechanisms and roles of selective autophagy in mammals. Nat Rev Mol Cell Biol 2022.

[9]

Zechner R, Madeo F, Kratky D. Cytosolic lipolysis and lipophagy: two sides of the same coin. Nat Rev Mol Cell Biol 2017;18:671–684.

[10]

Zhao YG, Codogno P, Zhang H. Machinery, regulation and pathophysiological implications of autophagosome maturation. Nat Rev Mol Cell Biol 2021;22:733–750.

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The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.

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