mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

Qun Chu; Feifei Liu; Yifang He; Xiaoyu Jiang; Yusheng Cai; Zeming Wu; Kaowen Yan; Lingling Geng; Yichen Zhang; Huyi Feng; Kaixin Zhou; Si Wang; Weiqi Zhang; Guang-Hui Liu; Shuai Ma; Jing Qu; Moshi Song

doi:10.1007/s13238-021-00898-9

Protein Cell ›› 2022, Vol. 13 ›› Issue (9) : 676 -682. DOI: 10.1007/s13238-021-00898-9

LETTER

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

Qun Chu ¹^,³^,⁴^,¹¹
, Feifei Liu ²^,³^,⁴
, Yifang He ²^,³^,⁴^,⁸
, Xiaoyu Jiang ²^,³^,⁴^,⁸
, Yusheng Cai ²^,³^,⁴
, Zeming Wu ²^,³^,⁴
, Kaowen Yan ²^,³^,⁴
, Lingling Geng ⁵^,⁹
, Yichen Zhang ²^,³^,⁴^,⁸
, Huyi Feng ¹¹
, Kaixin Zhou ¹²
, Si Wang ⁵^,⁹
, Weiqi Zhang ³^,⁵^,⁶^,⁷^,⁸^,⁹^,¹⁰
, Guang-Hui Liu ²^,³^,⁴^,⁵^,⁸^,⁹^,^†
, Shuai Ma ²^,³^,⁴^,^†
, Jing Qu ¹^,³^,⁴^,⁸^,^†
, Moshi Song ²^,³^,⁴^,⁸^,^†

Author information +

¹. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

². State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

³. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China

⁴. Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China

⁵. Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China

⁶. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China

⁷. China National Center for Bioinformation, Beijing 100101, China

⁸. University of Chinese Academy of Sciences, Beijing 100049, China

⁹. Aging Translational Medicine Center, International Center for Aging and Cancer, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

¹⁰. Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China

¹¹. Chongqing Renji Hospital, University of Chinese Academy of Sciences, Chongqing 400062, China

¹². College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China

ghliu@ioz.ac.cn

mashuai@ioz.ac.cn

qujing@ioz.ac.cn

songmoshi@ioz.ac.cn

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Qun Chu, Feifei Liu, Yifang He, Xiaoyu Jiang, Yusheng Cai, Zeming Wu, Kaowen Yan, Lingling Geng, Yichen Zhang, Huyi Feng, Kaixin Zhou, Si Wang, Weiqi Zhang, Guang-Hui Liu, Shuai Ma, Jing Qu, Moshi Song. mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells. Protein Cell, 2022, 13(9): 676-682 DOI:10.1007/s13238-021-00898-9

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