PINK1 mediates neuronal survival in monkey

Zhiyu Sun , Jiangyu Ye , Junying Yuan

Protein Cell ›› 2022, Vol. 13 ›› Issue (1) : 4 -5.

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Protein Cell ›› 2022, Vol. 13 ›› Issue (1) : 4 -5. DOI: 10.1007/s13238-021-00889-w
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PINK1 mediates neuronal survival in monkey

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Zhiyu Sun, Jiangyu Ye, Junying Yuan. PINK1 mediates neuronal survival in monkey. Protein Cell, 2022, 13(1): 4-5 DOI:10.1007/s13238-021-00889-w

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Cummins N, Gotz J (2018) Shedding light on mitophagy in neurons:what is the evidence for PINK1/Parkin mitophagy in vivo? Cell Mol Life Sci 75: 1151- 1162

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Okatsu K, Oka T, Iguchi M, Imamura K, Kosako H, Tani N, Kimura M, Go E, Koyano F, Funayama M (2012) PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat Commun 3: 1016

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Picconi B, Piccoli G, Calabresi P (2012) Synaptic dysfunction in Parkinson’s disease. Adv Exp Med Biol 970: 553- 572

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Pickrell AM, Youle RJ (2015) The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson’s disease. Neuron 85: 257- 273

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Yang W, Li S, Li XJ (2019) A CRISPR monkey model unravels a unique function of PINK1 in primate brains. Mol Neurodegener 14: 17

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Yang W, Guo X, Tu Z, Chen X, Han R, Liu Y, Yan S, Wang Q, Wang Z, Zhao X (2021) PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis. Protein Cell.

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