Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19

Lunzhi Yuan; Huachen Zhu; Ming Zhou; Jian Ma; Rirong Chen; Liuqin Yu; Wenjia Chen; Wenshan Hong; Jia Wang; Yao Chen; Kun Wu; Wangheng Hou; Yali Zhang; Shengxiang Ge; Yixin Chen; Quan Yuan; Qiyi Tang; Tong Cheng; Yi Guan; Ningshao Xia

doi:10.1007/s13238-021-00874-3

PDF(979 KB)

Protein Cell ›› 2022, Vol. 13 ›› Issue (1) : 72-77. DOI: 10.1007/s13238-021-00874-3

LETTER

Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19

Lunzhi Yuan¹ ,
Huachen Zhu²^,³ ,
Ming Zhou¹ ,
Jian Ma¹ ,
Rirong Chen²^,³ ,
Liuqin Yu²^,³ ,
Wenjia Chen²^,³ ,
Wenshan Hong²^,³ ,
Jia Wang²^,³ ,
Yao Chen¹ ,
Kun Wu¹ ,
Wangheng Hou¹ ,
Yali Zhang¹ ,
Shengxiang Ge¹ ,
Yixin Chen¹ ,
Quan Yuan¹ ,
Qiyi Tang⁴ ,
Tong Cheng¹ ,
Yi Guan¹ ,
Ningshao Xia¹^,⁵

Author information +

History +

Cite this article

EndNote

Ris (Procite)

Bibtex

Download citation ▾

Lunzhi Yuan, Huachen Zhu, Ming Zhou, Jian Ma, Rirong Chen, Liuqin Yu, Wenjia Chen, Wenshan Hong, Jia Wang, Yao Chen, Kun Wu, Wangheng Hou, Yali Zhang, Shengxiang Ge, Yixin Chen, Quan Yuan, Qiyi Tang, Tong Cheng, Yi Guan, Ningshao Xia. Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19. Protein Cell, 2022, 13(1): 72‒77 https://doi.org/10.1007/s13238-021-00874-3

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	An J, Liao X, Xiao T, Qian S, Yuan J, Ye H, Qi F, Shen C, Wang L, Liu Y(2020) Clinical characteristics of recovered COVID-19 patients with re-detectable positive RNA test. Ann Transl Med 8:1084 CrossRef Google scholar

[2]	Carfi A, Bernabei R, Landi F, Gemelli Against C-P-ACSG(2020) Persistent symptoms in patients after acute COVID-19. JAMA 324:603–605 CrossRef Google scholar

[3]

Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L(2020) Simulation of the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) in a Golden Syrian Hamster Model: implications for disease pathogenesis and transmissibility. Clin Infect Dis 71:2428–2446

CrossRef Google scholar

[4]	Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, Qiu Y, Wang J, Liu Y, Wei Y(2020) Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 395:507–513 CrossRef Google scholar

[5]	Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, Kang L, Guo L, Liu M, Zhou X(2021) 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet 397:220–232 CrossRef Google scholar

[6]	Imai M, Iwatsuki-Horimoto K, Hatta M, Loeber S, Halfmann PJ, Nakajima N, Watanabe T, Ujie M, Takahashi K, Ito M(2020) Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development. Proc Natl Acad Sci USA 117:16587–16595 CrossRef Google scholar

[7]	Kim MC, Cui C, Shin KR, Bae JY, Kweon OJ, Lee MK, Choi SH, Jung SY, Park MS, Chung JW(2021) Duration of culturable SARS-CoV-2 in hospitalized patients with Covid-19. N Engl J Med 384:671–673 CrossRef Google scholar

[8]	Lim ST, Janaway B, Costello H, Trip A, Price G(2020) Persistent psychotic symptoms following COVID-19 infection. Bjpsych Open 6:e105 CrossRef Google scholar

[9]	Sia SF, Yan LM, Chin AWH, Fung K, Choy KT, Wong AYL, Kaewpreedee P, Perera R, Poon LLM, Nicholls JM(2020) Pathogenesis and transmission of SARS-CoV-2 in golden hamsters. Nature 583:834–838 CrossRef Google scholar

[10]	Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y(2020) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 323:1061–1069 CrossRef Google scholar

[11]	Yao XH, He ZC, Li TY, Zhang HR, Wang Y, Mou H, Guo Q, Yu SC, Ding Y, Liu X(2020) Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient. Cell Res 30:541–543 CrossRef Google scholar

[12]	Yuan L, Tang Q, Cheng T, Xia N(2020) Animal models for emerging coronavirus: progress and new insights. Emerg Microbes Infect 9:949–961 CrossRef Google scholar

[13]	Yuan L, Zhu H, Zhou M, Ma J, Chen R, Chen Y, Chen L, Wu K, Cai M, Hong J(2021) Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster. Signal Transduct Target Ther 6:136 CrossRef Google scholar

[14]	Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R(2020) A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 382:727–733 CrossRef Google scholar