Structure of African swine fever virus p15 reveals its dual role for membrane-association and DNA binding

Dan Fu; Dongming Zhao; Wei Zhang; Guangshun Zhang; Mingyu Li; Zheng Zhang; Yuhui Wang; Dongdong Sun; Peng Jiao; Cheng Chen; Yu Guo; Zihe Rao

doi:10.1007/s13238-020-00731-9

PDF(1310 KB)

Protein Cell ›› 2020, Vol. 11 ›› Issue (8) : 606-612. DOI: 10.1007/s13238-020-00731-9

LETTER

Structure of African swine fever virus p15 reveals its dual role for membrane-association and DNA binding

Author information +

History +

Cite this article

EndNote

Ris (Procite)

Bibtex

Download citation ▾

Dan Fu, Dongming Zhao, Wei Zhang, Guangshun Zhang, Mingyu Li, Zheng Zhang, Yuhui Wang, Dongdong Sun, Peng Jiao, Cheng Chen, Yu Guo, Zihe Rao. Structure of African swine fever virus p15 reveals its dual role for membrane-association and DNA binding. Protein Cell, 2020, 11(8): 606‒612 https://doi.org/10.1007/s13238-020-00731-9

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Andres G, Alejo A, Salas J, Salas ML (2002) African swine fever virus polyproteins pp220 and pp62 assemble into the core shell. J Virol 76:12473–12482 CrossRef Google scholar

[2]	Andres G, Charro D, Matamoros T, Dillard RS, Abrescia NGA (2020) The cryo-EM structure of African swine fever virus unravels a unique architecture comprising two icosahedral protein capsids and two lipoprotein membranes. J Biol Chem 295:1–12 CrossRef Google scholar

[3]	Andres G, Garcia-Escudero R, Vinuela E, Salas ML, Rodriguez JM (2001) African swine fever virus structural protein pE120R is essential for virus transport from assembly sites to plasma membrane but not for infectivity. J Virol 75:6758–6768 CrossRef Google scholar

[4]	Hill CP, Worthylake D, Bancroft DP, Christensen AM, Sundquist WI (1996) Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly. Proc Natl Acad Sci USA 93:3099–3104 CrossRef Google scholar

[5]	Holm L, Sander C (1995) Dali: a network tool for protein structure comparison. Trends Biochem Sci 20:478–480 CrossRef Google scholar

[6]	Iyer LM, Aravind L, Koonin EV (2001) Common origin of four diverse families of large eukaryotic DNA viruses. J Virol 75:11720–11734 CrossRef Google scholar

[7]	Liu S, Luo Y, Wang Y, Li S, Zhao Z, Bi Y, Sun J, Peng R, Song H, Zhu D (2019) Cryo-EM structure of the African swine fever virus. Cell Host Microbe 26(836–843):e833 CrossRef Google scholar

[8]	Rao Z, Belyaev AS, Fry E, Roy P, Jones IM, Stuart DI (1995) Crystal structure of SIV matrix antigen and implications for virus assembly. Nature 378:743–747 CrossRef Google scholar

[9]	Ruigrok RW, Barge A, Durrer P, Brunner J, Ma K, Whittaker GR (2000) Membrane interaction of influenza virus M1 protein. Virology 267:289–298 CrossRef Google scholar

[10]	Seifert GJ (2018) Fascinating fasciclins: a surprisingly widespread family of proteins that mediate interactions between the cell exterior and the cell surface. Int J Mol Sci 19:E1628 CrossRef Google scholar

[11]	Sha B, Luo M (1997) Structure of a bifunctional membrane-RNA binding protein, influenza virus matrix protein M1. Nat Struct Biol 4:239–244 CrossRef Google scholar

[12]	Simon-Mateo C, Andres G, Almazan F, Vinuela E (1997) Proteolytic processing in African swine fever virus: evidence for a new structural polyprotein, pp62. J Virol 71:5799–5804 CrossRef Google scholar

[13]	Simon-Mateo C, Andres G, Vinuela E (1993) Polyprotein processing in African swine fever virus: a novel gene expression strategy for a DNA virus. EMBO J 12:2977–2987 CrossRef Google scholar

[14]	Suarez C, Salas ML, Rodriguez JM (2010) African swine fever virus polyprotein pp62 is essential for viral core development. J Virol 84:176–187 CrossRef Google scholar

[15]	Wang N, Zhao D, Wang J, Zhang Y, Wang M, Gao Y, Li F, Wang J, Bu Z, Rao Z (2019) Architecture of African swine fever virus and implications for viral assembly. Science 366:640–644 CrossRef Google scholar